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Atuzaginstat
go.drugbank.com/drugs/DB19030InvestigationalAtuzaginstat is under investigation in clinical trial NCT03823404 (GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease).
Synonyms: N-((3s)-7-amino-2-oxo-1-(2,3,6- trifluorophenoxy)heptan-3-yl)cyclopentanecarboxamide, Cyclopentanecarboxamide, n-((1s)-5-amino-1-(2-(2,3,6-trifluorophenoxy)acetyl)pentyl)-Mevidalen
go.drugbank.com/drugs/DB19034InvestigationalMevidalen is under investigation in clinical trial NCT03305809 (A Study of LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or
Synonyms: 2-(2,6-dichlorophenyl)-1-((1s,3r)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2(1h)-yl)ethanone, Ethanone, 2-(2,6-dichlorophenyl)-1-((1s,3r)-3,4-dihydro-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-2(1h)-isoquinolinyl)-Categories: Heterocyclic Compounds, 2-RingBNC-210
go.drugbank.com/drugs/DB19048InvestigationalBNC-210 is under investigation in clinical trial NCT04951076 (A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-traumatic Stress Disorder (PTSD)).
Synonyms: 1,8-NAPHTHYRIDIN-4(1H)-ONE, 6-((2,3-DIHYDRO-1H-INDEN-2-YL)AMINO)-1-ETHYL-3-(4-MORPHOLINYLCARBONYL)-, 6-((2,3-dihydro-1h-inden-2-yl)amino)-1-ethyl-3-(4-morpholinylcarbonyl)-1,8-naphthyridin-4(1h)-oneRenvistobart
go.drugbank.com/drugs/DB19065InvestigationalRenvistobart is under investigation in clinical trial NCT02913313 (A Study of BMS-986207 Given Alone and in Combination With Nivolumab or With Nivolumab and Ipilimumab in Advanced Solid Tumors).
Lerodalcibep
go.drugbank.com/drugs/DB19071ApprovedInvestigationalLerodalcibep is a recombinant fusion protein that binds to and inhibits proprotein convertase subtilisin kexin type 9 (PCSK9). … [L54738] PCSK9 is a protein that binds to and promotes the degradation of low-density lipoprotein receptors (LDLRs), which are expressed on hepatocytes regulates circulating LDL levels.
Synonyms: Engineered binding protein (1-96) anti-(human proprotein convertase subtilisin/kexin type 9), derived from human tenth fibronectin type iii domain, fused via peptidyl linker (97gsgsgs102) to human serum, Protein lib003 (recombinant human proprotein convertase subtilisin/kexin type 9 ligand-binding tenth fibronectin type iii domain) fusion protein with peptide (synthetic 6-amino acid linker) fusion proteinCategories: Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsModified vaccinia virus Ankara-85A antigen
go.drugbank.com/drugs/DB19092InvestigationalModified vaccinia virus Ankara-85A antigen is under investigation in clinical trial NCT00953927 (A Study of MVA85A in Healthy Infants).
SPH-3127
go.drugbank.com/drugs/DB19108InvestigationalSPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety of SPH3127 in Patients With Mild-moderate Essential Hypertension).
Synonyms: CARBAMIC ACID, N-(3-(3-((1R)-1-(CYCLOPROPYL((2R)-2-MORPHOLINYLCARBONYL)AMINO)ETHYL)-6-METHYL-1H-PYRAZOLO(3,4-B)PYRIDIN-1-YL)PROPYL)-, METHYL ESTERCategories: Heterocyclic Compounds, 1-RingKER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Synonyms: QUINOLINE, 7-FLUORO-6-METHOXY-4-(6-(4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)PYRAZOLO(1,5-A)PYRIMIDIN-3-YL)-Timbetasin
go.drugbank.com/drugs/DB19119InvestigationalTimbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Synonyms: N-ACETYL-L-SERYL-L-ASPARTYL-L-LYSYL-L-PROLYL-L-ASPARTYL-L-METHIONYL-L-ALANYL-L-GLUTAMYL-L-ISOLEUCYL-L-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-ASPARTYL-L-LYSYL-L-SERYL-L-LYSYL-L-LEUCYL-L-LYSYL-L-LYSYL-L-THEONYL-L-GLUTAMYL-L-THEONYL-L-GLUTAMINYL-L-GLUTAMYL-L-LYS, L-SERINE, N-ACETYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-LYSYL-L-PROLYL-L-.ALPHA.-ASPARTYL-L-METHIONYL-L-ALANYL-L-.ALPHA.-GLUTAMYL-L-ISOLEUCYL-L-.ALPHA.-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-.ALPHA.Redasemtide
go.drugbank.com/drugs/DB19121InvestigationalRedasemtide is under investigation in clinical trial NCT05953480 (A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke).