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Nicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalA potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: NİCARDİPİNE AGUETTANT 10 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 10 ADET- HASTANE AMBALAJI, NINAX 25 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL ,10 AMPULEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approvedThe primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle. … [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%).
Mixtures: DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET, DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesEtoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnIt is approved in more than 60 countries worldwide but not in the US. … Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid.
Mixtures: ETRAL - TRCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesThiopental
go.drugbank.com/drugs/DB00599ApprovedInvestigationalVet approvedWithdrawnIt has been used in neurosurgical patients to reduce increased intracranial pressure. It does not produce any excitation but has poor analgesic and muscle relaxant properties. … Small doses have been shown to be anti-analgesic and lower the pain threshold. (From Martindale, The Extra Pharmacopoeia, 30th ed, p920)
Synonyms: 2-Thio-5-ethyl-5-sec-pentylbarbituric acid, 5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersLisinopril
go.drugbank.com/drugs/DB00722ApprovedInvestigationalLisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction. … [A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.
Mixtures: Co-Lisinostad 10 mg/12,5 mg Tabletten, AMLIPIN 10 / 10 MG FILM TABLET, 30 ADETProducts: DAPRIL 10 TABLET 10 mg, LISORIL 10 TABLET 10 mgEtilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnEtilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Products: ETILEFRINACLORHIDRATO 10 MG /ML, ETILEFRINA CLORHIDRATO 10 MG/ MLMilnacipran
go.drugbank.com/drugs/DB04896ApprovedInvestigationalMilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment … Moreover, recent research has shown that the levorotatory enantiomer of milnacipran, levomilnacipran, may have the capacity to inhibit the activity of beta-site amyloid precursor protein cleaving enzyme
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: IXEL 50 MG KAPSUL, 56 ADET, Ixel 50 mg - KapselnPeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalPeramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. … Due to the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and Johnson Company.
Products: Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (10 Adet), Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (5 Adet)Alfentanil
go.drugbank.com/drugs/DB00802ApprovedIllicitInvestigationalA short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analges...
Synonyms: N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilideCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesFulvestrant
go.drugbank.com/drugs/DB00947ApprovedInvestigationalIt is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.
Synonyms: (7α,17β)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates