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Alintegimod
go.drugbank.com/drugs/DB18879InvestigationalAlintegimod is under investigation in clinical trial NCT06362369 (A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy).
Eltrekibart
go.drugbank.com/drugs/DB19017InvestigationalEltrekibart is under investigation in clinical trial NCT06046729 (A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).
CH-1504 L-isomer
go.drugbank.com/drugs/DB19052InvestigationalCH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Synonyms: 4-methylene-n-(4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)-l-glutamic acid, L-glutamic acid, n-(4-(2-(2,4-diamino-6-quinazolinyl)ethyl)benzoyl)-4-methylene-Evexomostat
go.drugbank.com/drugs/DB19140InvestigationalEvexomostat is under investigation in clinical trial NCT05570253 (A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer).
Synonyms: Poly((n-(2-hydroxypropyl)methacrylamide)-co-(methacryloyl-gly-phe-leu-gly amide with o-((trans-4-aminocyclohexyl)carbamoyl)fumagillol)) (~0.91:0.09 x)Vecabrutinib
go.drugbank.com/drugs/DB16657InvestigationalVecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).
Categories: Heterocyclic Compounds, 1-RingUbamatamab
go.drugbank.com/drugs/DB18875InvestigationalUbamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent
Synonyms: Bispecific t-cell engager antibody regn4018, Muc16xcd3 bispecific t-cell engager regn4018Tifcemalimab
go.drugbank.com/drugs/DB18914InvestigationalTifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell
Synonyms: Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 .gamma.4-chain), disulfide with human-mus musculus monoclonal js004 .kappa.-chain, dimerN-Formylmethionine
go.drugbank.com/drugs/DB04464ExperimentalN-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. … This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.
Synonyms: L-N-Formylmethionine, N-formyl-L-methionineBecotatug
go.drugbank.com/drugs/DB19069InvestigationalBecotatug is under investigation in clinical trial NCT06380348 (JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung
Synonyms: Immunoglobulin G1, anti-(human epidermal growth factor receptor) (human-Mus musculus monoclonal JMT101 γ1-chain), disulfide with human-Mus musculus monoclonal JMT101 κ-chain, dimerAMY-101
go.drugbank.com/drugs/DB14803InvestigationalAMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis). … AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3.
Synonyms: S3,S13-Cyclo(D-tyrolsyl-L-isoleucyl-L-cysteinyl-L-valyl-1-methyl-L-tryptophyl-L-glutaminyl-L-aspartyl-L-tryptophyl-N-methyl-L-glycyl-L-alanyl-L-histidyl-L-arginyl-L-cysteinyl-N-methyl-L-isoleucinamide)