Search

Displaying results 9141 - 9150 of 10000 in total
  1. Drug

    PRX-07034

    go.drugbank.com/drugs/DB05993
    Experimental

  2. Drug

    Inolimomab

    go.drugbank.com/drugs/DB15628
    Investigational

    It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385] … Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease.

  3. Drug

    Selisistat

    go.drugbank.com/drugs/DB13978
    Investigational

    Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3 … Enhances p53 acetylation in response to DNA damaging agents.

  4. Drug

    Apatorsen

    go.drugbank.com/drugs/DB06094
    Investigational

    Apatorsen is a second generation antisense drug which in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human cancers

  5. Drug

    Epibatidine

    go.drugbank.com/drugs/DB07720
    Experimental

    Categories: Analgesics, Non-Narcotic
  6. Drug

    Tamnorzatinib

    go.drugbank.com/drugs/DB19201
    Investigational

    Tamnorzatinib is under investigation in clinical trial NCT03176277 (A Study of ONO-7475 in Patients With Acute Leukemias).

    Synonyms: 3-quinolinecarboxamide, n-(5-((6,7-dimethoxy-4-quinolinyl)oxy)-2-pyridinyl)-1,2,5,6,7,8-hexahydro-2,5-dioxo-1-phenyl-, N-(5-((6,7-dimethoxyquinolin-4-yl)oxy)pyridin-2-yl)-2,5-dioxo-1-phenyl-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide
  7. Drug

    RGN6024

    go.drugbank.com/drugs/DB33059
    Experimental

    RGN6024, also known as RGN-6024 or RGNi6024, is a synthetic small-molecule tubulin destabilizer from Reglagene. … Preclinical characterization reports that RGN6024 binds the colchicine-binding site of beta-tubulin, inhibits microtubule polymerization in biochemical and cellular assays, induces G2/M arrest in glioblastoma

  8. Drug

    Mebenil

    go.drugbank.com/drugs/DB14728
    Experimental

    An obsolete fungicide used to control various pathogens on cereals and seed potatoes.

    Synonyms: o-Toluanilide, o-Methylbenzanilide
  9. Drug

    Neopterin

    go.drugbank.com/drugs/DB15050
    Investigational

    Neopterin is under investigation in clinical trial NCT02974192 (Neopterin Effects on Ischemic Stroke).

  10. Drug

    TERN-101

    go.drugbank.com/drugs/DB16045
    Investigational

    TERN-101 is under investigation in clinical trial NCT04328077 (LIFT Study: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of TERN-101 in Subjects With Non-cirrhotic Non-alcoholic Steatohepatitis