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Lisdexamfetamine
go.drugbank.com/drugs/DB01255ApprovedInvestigationalLisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine.
Products: SAMEXID® 50MG, SAMEXID® 30 MGRetapamulin
go.drugbank.com/drugs/DB01256ApprovedRetapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ALTARGO UNGUENTO 1%Desonide
go.drugbank.com/drugs/DB01260ApprovedInvestigationalA nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Mixtures: SPORUM-D, APOLAR NCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersDecitabine
go.drugbank.com/drugs/DB01262ApprovedInvestigationalFurther mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis. … Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one, 5-aza-2'-deoxycytidinePosaconazole
go.drugbank.com/drugs/DB01263ApprovedInvestigationalVet approvedPosaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: NOXAFIL® SUSPENSION ORAL., POSIOLE® IV SOLUCIÓN PARA INFUSIÓN 300 MG/16.7 MLTelbivudine
go.drugbank.com/drugs/DB01265ApprovedWithdrawnTelbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus.
Categories: Heterocyclic Compounds, 1-Ring, Hepatitis B Virus Nucleoside Analog Reverse Transcriptase InhibitorSynonyms: 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil, β-L-2'-deoxythymidinePanitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent.
Products: VECTIBIX® 20 MG/ ML, VECTIBIX 20 MG/ML 5 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADETMecasermin
go.drugbank.com/drugs/DB01277ApprovedInvestigationalThe rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1. … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons.
Categories: Recombinant Human Insulin-like Growth Factor-1Synonyms: VEXXON-IGF-1, Human somatomedin CGalsulfase
go.drugbank.com/drugs/DB01279ApprovedInvestigationalGalsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular
Synonyms: N-acetylgalactosamine-4-sulfatase, recombinant human, Arylsulfatase B galsulfaseProducts: NAGLAZYME®Abatacept
go.drugbank.com/drugs/DB01281ApprovedInvestigationalAbatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human … The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes.
Categories: Selective T Cell Costimulation ModulatorProducts: ORENCIA® SOLUCION INYECTABLE PARA ADMINISTRACION SUBCUTÁNEA 125 MG/ML, ORENCIA® 250 MG - POLVO LIOFILIZADO PARA SOLUCIÓN INYECTABLE INTRAVENOSA