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Geptanolimab
go.drugbank.com/drugs/DB16417InvestigationalGeptanolimab is under investigation in clinical trial NCT03502629 (Clinical Trial in Chinese Patients of Relapsed and Refractory Peripheral T Cell Lymphoma (GB226)).
Etentamig
go.drugbank.com/drugs/DB17268InvestigationalTNB-383B is a CD3 and B-cell maturation antigen T-cell engaging bispecific antibody.
Synonyms: Anti-BCMA x aCD3 T-BsAb TNB-383B, Anti-BCMA/Anti-CD3 T-cell Engaging Bispecific Antibody ABBV-383AMG-119
go.drugbank.com/drugs/DB17363InvestigationalAMG-119 are CAR-T cells targeting delta-like ligand 3 (DLL3).[A254811]
LioCyx-M004
go.drugbank.com/drugs/DB17368InvestigationalLioCyx-M004 are autologous T cells transduced with a retroviral vector encoding a hepatitis B virus antigen-specific T cell receptor.
Synonyms: mRNA HBV/TCR T-cellsP-BCMA-101
go.drugbank.com/drugs/DB17371InvestigationalP-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Synonyms: Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen (CAR-T cells)KITE-585
go.drugbank.com/drugs/DB17409InvestigationalKITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.
CK0802
go.drugbank.com/drugs/DB15866Investigational[L16358] On the surface of these T-Reg cells, T-cell lung homing markers are expressed. … CK0802 is an off-the-shelf product composed of allogeneic umbilical cord blood derived regulatory T-cells (T-Reg cells), which can be used intravenously and without HLA matching.
Synonyms: Allogeneic Umbilical Cord Blood Derived Regulatory T-CellsPeptide-T
go.drugbank.com/drugs/DB19279InvestigationalPeptide-T is under investigation in clinical trial NCT00000392 (Phase II Study of the Efficacy of Peptide T in Hiv-positive Individuals With Cognitive Impairment.).
Synonyms: Peptide T, Peptide-TPactimibe
go.drugbank.com/drugs/DB12971InvestigationalPactimibe has been used in trials studying the treatment of Atherosclerosis and Coronary Heart Disease.
Categories: Sterol O-Acyltransferase, antagonists & inhibitorsST-101
go.drugbank.com/drugs/DB12621InvestigationalST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.[A260411]