Pactimibe

DB12971InvestigationalSmall molecule

Pactimibe has been used in trials studying the treatment of Atherosclerosis and Coronary Heart Disease.

Mechanism: Pharmacologically active on Sterol O-acyltransferase 1 and Sterol O-acyltransferase 2
Curator reviewed
Formula / weight: C₂₅H₄₀N₂O₃ · 416.606 g/mol (avg)

Resolves to

Compound

Clinical / RWD

Structure

InChIKeyTXIIZHHIOHVWJD-UHFFFAOYSA-NSMILESCCCCCCCCN1CCC2=C1C(NC(=O)C(C)(C)C)=C(C)C(CC(O)=O)=C2C

Targets

What you can answer from here — as of June 15, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pactimibe, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.