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5-Aminouracil
go.drugbank.com/drugs/DB03792ExperimentalCategories: Heterocyclic Compounds, 1-RingSynonyms: 5-Amino-2,4-dihydroxypyrimidine, 5-aminopyrimidine-2,4(1H,3H)-dioneGadoxetic acid
go.drugbank.com/drugs/DB08884ApprovedInvestigationalEthoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. … Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection.
Categories: Compounds used in a research, industrial, or household settingProducts: PRIMOVIST® SOLUCIÓN INYECTABLE, PRIMOVIST 0,25 MMOL/ML ENJEKSIYON ICIN COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADETArbaclofen
go.drugbank.com/drugs/DB08891InvestigationalIt is believed to be a selective gamma-amino butyric acid type B receptor agonist, and has been investigated as a treatment for autism spectrum disorder and fragile X syndrome in randomized, double blind … Arbaclofen, or STX209, is the R-enantiomer of baclofen.
Synonyms: (R)-4-amino-3-(4-chlorophenyl)butanoic acid, (R)-BaclofenPeginesatide
go.drugbank.com/drugs/DB08894ApprovedWithdrawnPeginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine. FDA approved March 27, 2012. … Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself.
Categories: Compounds used in a research, industrial, or household settingGlucarpidase
go.drugbank.com/drugs/DB08898ApprovedInvestigationalGlucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified _Escherichia coli_ bacteria. It is a 390-amino acid homodimer protein. … [A7476,A7477] After the discovery of certain bacteria with the capacity to inactivate folate analogs such as methotrexate, carboxypeptidase G was identified and Carboxypeptidase G1 was first isolated
Certolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigational[A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. … Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha).
Products: CIMZIA®, CIMZIA 200MG PAT F DOSIERGGlycerol phenylbutyrate
go.drugbank.com/drugs/DB08909ApprovedInvestigationalGlycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: Glyceryl Tri-4-PhenylbutyratePomalidomide
go.drugbank.com/drugs/DB08910ApprovedInvestigationalFDA approved on February 8, 2013.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: POMALYST® 4 MG, POMALYST ® 1 MGRadium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalAs a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. … Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles.
Products: XOFIGO®, XOFIGO 1100 KBQ/ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON,1 ADETAmperozide
go.drugbank.com/drugs/DB08927ExperimentalAmperozide is a diphenylbutylpiperazine atypical antipsychotic which antagonizes 5-HT2A receptors. It inhibits dopamine release and alters the firing of dopaminergic neurons.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor Antagonists