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Displaying results 9211 - 9220 of 10000 in total
  1. Drug

    IMVT-1402

    go.drugbank.com/drugs/DB21979
    Investigational

    IMVT-1402 is under investigation in clinical trial NCT06754462 (A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid

  2. Drug

    Azelaprag

    go.drugbank.com/drugs/DB19329
    Investigational

    Azelaprag is under investigation in clinical trial NCT06515418 (Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared With Tirzepatide Alone in Participants With Obesity Aged 55 Years

    Synonyms: 2-pyrimidineethanesulfonamide, n-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4h-1,2,4-triazol-3-yl)-.alpha.,.beta.,5-trimethyl-, (.alpha.s,.beta.r)-
  3. Drug

    L-lysyl-l-arginine

    go.drugbank.com/drugs/DB19436
    Investigational

    L-lysyl-l-arginine is under investigation in clinical trial NCT03972488 (Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET).

  4. Drug

    2-Hydroxyestradiol

    go.drugbank.com/drugs/DB07706
    Experimental

    2-Hydroxyestradiol is classified as an endogenous steroid, catechol estrogen, and metabolite of estradiol. It is also a positional isomer of estriol. [A31630]

  5. Drug

    Tarextumab

    go.drugbank.com/drugs/DB12104
    Investigational

    Tarextumab has been used in trials studying the treatment of Solid Tumors, Stage IV Pancreatic Cancer, and Stage IV Small Cell Lung Cancer.

  6. Drug

    GX-19 Vaccine

    go.drugbank.com/drugs/DB15891
    Investigational

    The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. … As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].

  7. Drug

    DTX-101

    go.drugbank.com/drugs/DB17699
    Investigational

    DTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene. … It was previously investigated for the treatment of hemophilia B; however, the clinical development of DTX-101 was discontinued.[L46103]

  8. Drug

    Retezorogant

    go.drugbank.com/drugs/DB21592
    Experimental

    The usage of the INN stem '-rogant' in the name indicates that Retezorogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist. … Retezorogant is a small molecule drug.

  9. Drug

    Anti-SARS-CoV-2 REGN-COV2

    go.drugbank.com/drugs/DB15691
    Investigational

    This drug is a combination of the antibodies REGN10933 and REGN10987, derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. … [L14303] Two upcoming publications in the journal, _Science_, will provide additional information about preclinical research with the Anti-SARS-COV-2 REGN-COV2 antibody cocktail.

  10. Drug

    AZD-7687

    go.drugbank.com/drugs/DB14949
    Investigational

    AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study).