Tarextumab

DB12104InvestigationalProtein Based Therapies

Tarextumab has been used in trials studying the treatment of Solid Tumors, Stage IV Pancreatic Cancer, and Stage IV Small Cell Lung Cancer.

Mechanism: Pharmacologically active on Neurogenic locus notch homolog protein 2 and Neurogenic locus notch homolog protein 3
Curator reviewed
Code names: OMP-59R5

Resolves to

Compound

Targets

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

381Drug interactionsStructured to mechanism, not free text

3Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Tarextumab, and which of those have an active Phase 3 trial?

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