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Neladalkib
go.drugbank.com/drugs/DB21712InvestigationalThe usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor. … Neladalkib is under investigation in clinical trial NCT06765109 (Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC).
Synonyms: an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles)PYX-201
go.drugbank.com/drugs/DB18382InvestigationalPYX-201 is an antibody-drug conjugate directed against the extra domain-B splice variant of fibronectin.
TUM012
go.drugbank.com/drugs/DB18652InvestigationalTUM012 is a synthetic polymer PEG conjugated to a phospholipid anchor (2-dipalmitoyl-sn-glycerol-3-phosphatidylethanolamine)
XEN-D0501
go.drugbank.com/drugs/DB18673InvestigationalXEN-D0501 is a tetrahydronaphthyl urea-based selective TRPV1 antagonist being investigated for the treatment of erythromelalgia.
Pexmetinib
go.drugbank.com/drugs/DB16294InvestigationalPexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab).
Tetrafluoroborate
go.drugbank.com/drugs/DB16340InvestigationalTetrafluoroborate is under investigation in clinical trial NCT02907073 (Positron Emission Tomography (PET) Imaging Studies With NIS Reporter).
Tusamitamab ravtansine
go.drugbank.com/drugs/DB17448InvestigationalTusamitamab ravtansine is an antibody-drug conjugate that targets carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5).
Crefmirlimab
go.drugbank.com/drugs/DB17577InvestigationalCrefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.
Synonyms: Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells)Bakuchiol
go.drugbank.com/drugs/DB16102InvestigationalBakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of Bakuchiol and Retinol).
Pifusertib
go.drugbank.com/drugs/DB15054InvestigationalTAS-117 is under investigation in clinical trial NCT03017521 (K-BASKET, TAS-117, PI3K/AKT Gene Aberration).