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Pradigastat
go.drugbank.com/drugs/DB12866InvestigationalPradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD).
Rivenprost
go.drugbank.com/drugs/DB16315InvestigationalRivenprost is under investigation in clinical trial NCT00296556 (Therapeutic Study of ONO-4819CD for Ulcerative Colitis).
JTC-801 free base
go.drugbank.com/drugs/DB17033ExperimentalAn antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.[A253027]
Synonyms: Benzamide, n-(4-amino-2-methyl-6-quinolinyl)-2-((4-ethylphenoxy)methyl)-RPI-MN
go.drugbank.com/drugs/DB17957ExperimentalRPI-MN is a detoxified or chemically modified alpha-cobratoxin with antiviral properties. … [A260132] Being developed by Nutra Pharma under the trade name PEPTERON, it is being investigated for the treatment of neurological and immune disorders.[L47107]
Synonyms: RPI-MNActinium Ac 225 Vipivotide tetraxetan
go.drugbank.com/drugs/DB23637Investigationalfor the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma). … Actinium Ac 225 Vipivotide Tetraxetan is under investigation in clinical trial NCT07150715 (Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy
Vafidemstat
go.drugbank.com/drugs/DB16446InvestigationalVafidemstat is under investigation in clinical trial NCT03867253 (Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease).
MLN3897
go.drugbank.com/drugs/DB06505ExperimentalMLN3897, a novel CCR1 inhibitor, disrupts osteoclast formation and blocks the interaction between multiple myeloma cells and osteoclasts.
Synonyms: (4S)-4-(4-CHLOROPHENYL)-1-((3E)-3-(9-(1-HYDROXY-1-METHYL-ETHYL)-5H-(1)BENZOXEPINO(3,4-B)PYRIDIN-11-YLIDENE)PROPYL)-3,3-DIMETHYL-PIPERIDIN-4-OLT487
go.drugbank.com/drugs/DB05474ExperimentalT487 is a small molecule chemokine receptor antagonist to correct or modify immune system responses. It binds selectively and potently to CXCR3. … The formulation is administered orally and has anti-inflammatory effects in conditions such as rheumatoid arthritis, inflammatory bowel disease and psoriasis.
Tomaralimab
go.drugbank.com/drugs/DB15415InvestigationalTomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Synonyms: Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion tissue injury, anti-Tlr2 monoclonal antibody OPN-305N-acetyl-alpha-neuraminic acid
go.drugbank.com/drugs/DB03721ExperimentalAn N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Synonyms: O-sialic acid, N-Acetyl-alpha-D-neuraminic acid