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Enfortumab vedotin
go.drugbank.com/drugs/DB13007ApprovedInvestigational[L10836] It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting chemotherapeutic agent, monomethyl auristatin E (MMAE), joined by a protease-cleavable … [L10836] Enfortumab vedotin was later approved by the European Commission on April 13, 2022.[L42000]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: PADCEV 20 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADET, PADCEV 30 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADETLFF-571
go.drugbank.com/drugs/DB13013InvestigationalLFF571 has been used in trials studying the treatment of Moderate Clostridium Difficile Infection.
Categories: Heterocyclic Compounds, 1-RingRovalpituzumab tesirine
go.drugbank.com/drugs/DB13017InvestigationalRovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others.
Categories: Heterocyclic Compounds, 2-RingLY-2874455
go.drugbank.com/drugs/DB13022InvestigationalLY2874455 has been used in trials studying the treatment of Advanced Cancer.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRamatroban
go.drugbank.com/drugs/DB13036InvestigationalRamatroban has been used in trials studying the treatment of Asthma.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-RingFenoverine
go.drugbank.com/drugs/DB13042InvestigationalFenoverine has been used in trials studying the treatment of Irritable Bowel Syndrome.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingPAC-1
go.drugbank.com/drugs/DB13048InvestigationalPAC-1 has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.
Synonyms: PAC-1, Procaspase activating compound 1Upamostat
go.drugbank.com/drugs/DB13052InvestigationalUpamostat has been used in trials studying the treatment of Pancreatic Cancer.
Categories: Heterocyclic Compounds, 1-RingCP-195543
go.drugbank.com/drugs/DB13053InvestigationalCP-195,543 has been used in trials studying the treatment of Arthritis, Rheumatoid.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingMLN8054
go.drugbank.com/drugs/DB13061InvestigationalMLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
Categories: Heterocyclic Compounds, 2-Ring