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Nemolizumab
go.drugbank.com/drugs/DB15252ApprovedInvestigationalNemolizumab is a humanized monoclonal modified immunoglobulin 2 (IgG2) antibody directed against interleukin-31 receptor alpha (IL-31RA),[L51159] which is an endogenous cytokine implicated in the pathophysiology
Synonyms: Immunoglobulin G2, anti-(interleukin 31 receptor A) (human-Mus musculus monoclonal CIM331 γ-chain), disulfide with human-Mus musculus monoclonal CIM331 κ-chain, dimer, )-IGHJ5*01) [8.8.14] (1-121) -Homo sapiens IGHG2*0Butafenacil
go.drugbank.com/drugs/DB15261ExperimentalButafenacil is under investigation in clinical trial NCT03760328 (Effect of Upper Airway Stimulation in Patients With Obstructive Sleep Apnea).
Categories: Heterocyclic Compounds, 1-RingLesinidase alfa
go.drugbank.com/drugs/DB15267InvestigationalLesinidase alfa is under investigation in clinical trial NCT02324049 (Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)).
Afabicin
go.drugbank.com/drugs/DB15268InvestigationalAfabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus).
Categories: Heterocyclic Compounds, 2-RingEdratide
go.drugbank.com/drugs/DB15272InvestigationalEdratide is under investigation in clinical trial NCT00203151 (A Study to Evaluate the Tolerability, Safety and Effectiveness of Edratide in the Treatment of Lupus).
Fluorofuranylnorprogesterone F-18
go.drugbank.com/drugs/DB15282InvestigationalFluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).
Synonyms: FFNP F-18, 19-NORPREGN-4-ENE-3,20-DIONE, 21-(FLUORO-18F)-16,17-((R)-(2-FURANYLMETHYLENE)BIS(OXY))-, (16.ALPHA.)-Sulopenem
go.drugbank.com/drugs/DB15284InvestigationalSulopenem is a penem antibacterial. It is marketed as the prodrug [sulopenem etzadroxil] in combination with [probenecid].[L51768]
Categories: Heterocyclic Compounds, 1-RingNumidargistat
go.drugbank.com/drugs/DB15286InvestigationalCB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors).
Categories: Heterocyclic Compounds, 1-RingElismetrep
go.drugbank.com/drugs/DB15287InvestigationalElismetrep is under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects).
Foliglurax
go.drugbank.com/drugs/DB15292InvestigationalFoliglurax is under investigation in clinical trial NCT02639221 (A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring