Foliglurax

DB15292InvestigationalSmall molecule

Foliglurax is under investigation in clinical trial NCT02639221 (A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study in...

Mechanism: Pharmacologically active on Metabotropic glutamate receptor 4
Curator reviewed
Formula / weight: C₂₃H₂₃N₃O₃S · 421.52 g/mol (avg)
Code names: PXT002331

Resolves to

Compound

UNIIFR50CP1D6WCAS1883329-53-0ChEMBLCHEMBL4089083

Structure

InChIKeyZTEDNASHAWNBKQ-NCELDCMTSA-NSMILESO\N=C1/C=C(OC2=C1C=C(CCCN1CCOCC1)C=C2)C1=CC2=C(C=CS2)C=N1

Targets

Q14833GRM4

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Foliglurax, and which of those have an active Phase 3 trial?

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