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Mavelertinib
go.drugbank.com/drugs/DB16228InvestigationalMavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).
Nevanimibe
go.drugbank.com/drugs/DB16254InvestigationalNevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).
DCVax-L
go.drugbank.com/drugs/DB17580InvestigationalDCVax-L is a personalized immunotherapy comprising an autologous vaccine with dendritic cells loaded _in vitro_ with autologous tumour lysate.
EF-022
go.drugbank.com/drugs/DB17768InvestigationalEF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Synonyms: EF 022WVE-003
go.drugbank.com/drugs/DB17870InvestigationalWVE-003 is an allele-selective antisense oligonucleotide that works to selectively reduce the toxic mutant huntingtin (mHTT) protein.[L46787]
PNT001
go.drugbank.com/drugs/DB18375InvestigationalPNT001 is a humanized IgG4 S228P monoclonal antibody targeting the cis conformation of the phosphorylated Thr231-Pro232 motif in tau.
AVB-001
go.drugbank.com/drugs/DB18452InvestigationalAVB-001 is an encapsulated, engineered human ARPE-19 cell line that constitutively expresses the native human IL-2 cytokine
Emicerfont
go.drugbank.com/drugs/DB12910InvestigationalEmicerfont has been used in trials studying the diagnostic and treatment of Social Anxiety Disorder and Irritable Bowel Syndrome (IBS).
Rosiptor
go.drugbank.com/drugs/DB13012InvestigationalAQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
1alpha-Hydroxyvitamin D5
go.drugbank.com/drugs/DB13097Investigational1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.