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CGI-1842
go.drugbank.com/drugs/DB12744InvestigationalJI-101 has been used in trials studying the treatment of Cancer, Colon Cancer, Neuroendocrine, Ovarian Cancer, and Advanced Solid Tumors.
Vosilasarm
go.drugbank.com/drugs/DB13939InvestigationalRAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.
U-0126
go.drugbank.com/drugs/DB17060ExperimentalU-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.[A253162]
PRX-OTC
go.drugbank.com/drugs/DB17680ExperimentalPRX-OTC is an intracellular enzyme replacement therapy designed to replace missing or defective enzyme in patients with ornithine transcarbamylase deficiency.
Dalcinonacog alfa
go.drugbank.com/drugs/DB17707InvestigationalIt is being investigated for the treatment of hemophilia B.[A259058]
SPL23-2
go.drugbank.com/drugs/DB17866ExperimentalSPL23-2 is an antisense oligonucleotide (ASO) targeting the W1282X nonsense mutation associated with a severe form of cystic fibrosis.[L46767]
OTOF-GT
go.drugbank.com/drugs/DB18129InvestigationalOTOF-GT is a dual vector AAV gene therapy being investigated for the restoration of hearing loss associated with otoferlin deficiency.
Lefitolimod
go.drugbank.com/drugs/DB15061InvestigationalLefitolimod is under investigation in clinical trial NCT03837756 (Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV).
Oleclumab
go.drugbank.com/drugs/DB15088InvestigationalOleclumab is under investigation in clinical trial NCT03819465 (A Study of Novel Anti-cancer Agents in Patients With Previously Untreated NSCLC).
Cesium
go.drugbank.com/drugs/DB15392InvestigationalCesium is under investigation in clinical trial NCT02794675 (Intraoperative Placement of Cesium-131 Permanent Interstitial Brachytherapy in Head and Neck Cancer).