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Perospirone
go.drugbank.com/drugs/DB08922InvestigationalIt also displays affinity towards 5HT1A receptors as a partial agonist. … It is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502].
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximideAmfecloral
go.drugbank.com/drugs/DB08924ExperimentalIt acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the N-substituent, in this case, yields a compound that is active … Amfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes.
Riociguat
go.drugbank.com/drugs/DB08931ApprovedInvestigationalRiociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. Treatment with riociguat costs USD $7,500 for 30 days of treatment.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminateMacitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.
Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASCategories: Endothelin A Receptor Antagonists, Endothelin B Receptor AntagonistsLetosteine
go.drugbank.com/drugs/DB08939ExperimentalLetosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Kebuzone
go.drugbank.com/drugs/DB08940InvestigationalKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
Mixtures: Rheumesser 3 ml - AmpullenCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingIndoprofen
go.drugbank.com/drugs/DB08951ApprovedWithdrawnA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingIbuproxam
go.drugbank.com/drugs/DB08955ApprovedWithdrawnIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
Categories: Non COX-2 selective NSAIDSSynonyms: p-Isobutylhydratropohydroxamic acidGlibornuride
go.drugbank.com/drugs/DB08962ApprovedWithdrawnGlibornuride is a sulfonylurea-type anti-diabetic drug.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesFluprednidene
go.drugbank.com/drugs/DB08970ExperimentalFluprednidene is a corticosteroid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers