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CIGB-258 peptide
go.drugbank.com/drugs/DB15809ExperimentalAs of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens
Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Idetrexed
go.drugbank.com/drugs/DB21469InvestigationalThe usage of the INN stem '-trexed' in the name indicates that Idetrexed is a antineoplastic; thymidilate synthetase inhibitor. … Idetrexed is under investigation in clinical trial NCT02360345 (Phase I Trial of ONX-0801 Once Weekly or Alternate Weekly). Idetrexed has a monoisotopic molecular weight of 647.22 Da.
Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate
go.drugbank.com/drugs/DB02937ExperimentalAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. [PubChem]
Etarfolatide
go.drugbank.com/drugs/DB11810InvestigationalEtarfolatide has been used in trials studying the treatment and diagnostic of Breast Neoplasms, Non Small Cell Lung Cancer, and Adenocarcinoma of the Lung.
Mipsagargin
go.drugbank.com/drugs/DB11813InvestigationalMipsagargin has been used in trials studying the treatment of Prostate Cancer, Prostatic Neoplasms, Advanced Solid Tumors, Glioblastoma Multiforme, and Hepatocellular Carcinoma, among others.
Epafipase
go.drugbank.com/drugs/DB16158InvestigationalEpafipase is under investigation in clinical trial NCT00037687 (Safety and Efficacy of Recombinant Human Platelet-activating Factor Acetylhydrolase for the Treatment of Severe Sepsis).
Etanidazole
go.drugbank.com/drugs/DB12736InvestigationalEtanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others.
Osugacestat
go.drugbank.com/drugs/DB12006InvestigationalOsugacestat (BMS-906024) has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma.
Synonyms: (2R,3S)-N1-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamideCI-1040
go.drugbank.com/drugs/DB12429InvestigationalCI-1040 has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Breast Neoplasms, Pancreatic Cancer, and Colorectal Cancer, among others.