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Methylthioinosine
go.drugbank.com/drugs/DB02896ExperimentalAn analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.
KAI-1455
go.drugbank.com/drugs/DB06064ExperimentalSeveral studies have demonstrated that epsilon PKC plays a key role in cytoprotection during periods of ischemia. … In preclinical studies, KAI-1455 showed a dramatic reduction in infarct size when delivered prior to the ischemic insult.
Cabiralizumab
go.drugbank.com/drugs/DB15082InvestigationalCabiralizumab is under investigation in clinical trial NCT03502330 (APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma).
Technetium Tc-99m epratuzumab
go.drugbank.com/drugs/DB15452ExperimentalTechnetium Tc-99m epratuzumab is under investigation in clinical trial NCT00003337 (Radiolabeled Monoclonal Antibody in the Detection and Staging of Patients With Non-Hodgkin's Lymphoma).
Brazikumab
go.drugbank.com/drugs/DB16115InvestigationalBrazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Dihydroxyacetone phosphate
go.drugbank.com/drugs/DB04326InvestigationalDihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse.
Crenolanib
go.drugbank.com/drugs/DB11832InvestigationalCrenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
Hexoprenaline
go.drugbank.com/drugs/DB08957ApprovedWithdrawnHexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
TD101
go.drugbank.com/drugs/DB06596InvestigationalTD101, a small interfering RNA (siRNA) designed for the treatment of pachyonychia congenita
Arecoline
go.drugbank.com/drugs/DB04365ExperimentalAn alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. … It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.