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Displaying results 9301 - 9310 of 10000 in total
  1. Drug

    Deoxyribonuclease I

    go.drugbank.com/drugs/DB16523
    Investigational

    Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7[A227723]. It is normally found in saliva, urine, pancreatic secretions, and blood[A227723]. … Currently, DNase I is being investigated against respiratory failure in COVID-19 in the clinical trial NCT04541979 (Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19).

  2. Drug

    Abivertinib

    go.drugbank.com/drugs/DB15327
    Investigational

    The study is expected to be completed in March 2021.[L17398] … Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK).

  3. Drug

    Nicotinamide Mononucleotide

    go.drugbank.com/drugs/DB03227
    Investigational

    A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem]

  4. Drug

    SS1(dsFv)-PE38

    go.drugbank.com/drugs/DB17579
    Investigational

    SS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma … SS1(dsFv)-PE38 is a recombinant anti-mesothelin immunotoxin.

  5. Drug

    Aminorex

    go.drugbank.com/drugs/DB01490
    ExperimentalIllicit

    Aminorex is an amphetamine-like anorectic agent. It may cause pulmonary hypertension.

  6. Drug

    Gimatecan

    go.drugbank.com/drugs/DB06721
    Investigational

    Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.

    Synonyms: (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O-(tert-butyl)-(E)-oxime
  7. Drug

    Zoalene

    go.drugbank.com/drugs/DB11480
    ExperimentalVet approved

    Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.

    Synonyms: Coccidine A
  8. Drug

    Pridopidine

    go.drugbank.com/drugs/DB11947
    Investigational

    Pridopidine has been used in trials studying the treatment of Huntington's Disease.

  9. Drug

    Placulumab

    go.drugbank.com/drugs/DB11983
    Investigational

    Placulumab has been used in trials studying the treatment of Rheumatoid Arthritis.

  10. Drug

    Evatanepag

    go.drugbank.com/drugs/DB12022
    Investigational

    Evatanepag has been used in trials studying the treatment of Tibial Fractures.