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Pegtarviliase
go.drugbank.com/drugs/DB18999InvestigationalPegtarviliase is under investigation in clinical trial NCT05154890 (A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency).
BMS-741672
go.drugbank.com/drugs/DB19004InvestigationalBMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).
Synonyms: N-(5-(ISOPROPYL(METHYL)AMINO)-2-(2-OXO-3-((6-(TRIFLUOROMETHYL)QUINAZOLIN-4-YL)AMINO)PYRROLIDIN-1-YL)CYCLOHEXYL)METHANESULFONAMIDEAtuzaginstat
go.drugbank.com/drugs/DB19030InvestigationalAtuzaginstat is under investigation in clinical trial NCT03823404 (GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease).
Synonyms: Cyclopentanecarboxamide, n-((1s)-5-amino-1-(2-(2,3,6-trifluorophenoxy)acetyl)pentyl)-, N-((3s)-7-amino-2-oxo-1-(2,3,6- trifluorophenoxy)heptan-3-yl)cyclopentanecarboxamideMethylone
go.drugbank.com/drugs/DB19192InvestigationalMethylone is under investigation in clinical trial NCT05741710 (A Study to Assess the use of Methylone in the Treatment of PTSD).
Synonyms: 3,4-methylenedioxy-n-methylcathinoneONO-5334
go.drugbank.com/drugs/DB19206InvestigationalONO-5334 is under investigation in clinical trial NCT00532337 (Controlled Study of ONO-5334 in Postmenopausal Women With Osteopenia or Osteoporosis).
Synonyms: N-((1S)-3-((2Z)-2-((4R)-3,4-DIMETHYL-1,3-THIAZOLIDIN-2-YLIDENE)HYDRAZINO)-2,3-DIOXO-1-(TETRAHYDRO-2H-PYRAN-4YL)PROPYL)CYCLOHEPTANECARBOXAMIDEVilastobart
go.drugbank.com/drugs/DB19327InvestigationalVilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors).
MVA-BN-brachyury-TRICOM vaccine
go.drugbank.com/drugs/DB17424InvestigationalMVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine. … It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad
Synonyms: MVA-BN-Brachyury, MVA-BN-Brachyury Prime VaccineATX-F8-117
go.drugbank.com/drugs/DB17712ExperimentalATX-F8-117 is an investigational peptide derived from Factor VIII. Developed by Apitope, it is being investigated for the treatment of hemophilia A.[L46163]
ABBV-514
go.drugbank.com/drugs/DB17586InvestigationalABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]
Maridebart Cafraglutide
go.drugbank.com/drugs/DB19339InvestigationalMaridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity
Synonyms: insulinotropic polypeptide receptor) [275-cysteine,295-cysteine,300-glycine,305-cysteine] (human γ1-chain), disulfide with human κ-chain, dimer, 275,275′-bis(thioether) with 7-37-glucagon-like peptide I