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Bevonescein
go.drugbank.com/drugs/DB19021InvestigationalBevonescein is under investigation in clinical trial NCT06227585 (Feasibility Study- REVEAL 475 for Bevonescein-assisted Nerve Visualization in Head & Neck Surgery).
Pegozafermin
go.drugbank.com/drugs/DB19062InvestigationalPegozafermin is under investigation in clinical trial NCT05852431 (To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia).
Ectoine
go.drugbank.com/drugs/DB19171InvestigationalEctoine is under investigation in clinical trial NCT03186755 (Clinical Evaluation of Hylo-dual Versus Patanol in Children With Seasonal Allergic Conjunctivitis).
Synonyms: (4s)-3,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acidOnvitrelin ucalontide
go.drugbank.com/drugs/DB19183InvestigationalOnvitrelin ucalontide is under investigation in clinical trial NCT01485848 (EP-100 Plus Paclitaxel Versus Paclitaxel Alone in Patients With Ovarian Cancer).
Synonyms: Ep-100 (conjugate of luteinizing hormone-releasing hormone with a cationic .alpha.-helical peptide for therapy of lhrh-expressing tumors)Streptodornase
go.drugbank.com/drugs/DB19273InvestigationalStreptodornase is under investigation in clinical trial NCT04252963 (Clinical Trial to Assess the Efficacy and Safety of MUCOLASE Tablet(streptokinase • Streptodornase)).
Categories: Deoxyribonuclease I, antagonists & inhibitorsProcizumab
go.drugbank.com/drugs/DB23041InvestigationalProcizumab is under investigation in clinical trial NCT06331884 (Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics/-Dynamics of AK1967 (Procizumab)).
AZD-6482
go.drugbank.com/drugs/DB14980InvestigationalAZD-6482 is under investigation in clinical trial NCT00688714 (Study to Investigate Safety and Tolerability of a Single Dose of AZD6482).
Categories: Heterocyclic Compounds, 1-Ring, Class Ia Phosphatidylinositol 3-Kinase, antagonists & inhibitorsSepantronium
go.drugbank.com/drugs/DB17062InvestigationalSepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis.[A253167]
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: 1h-naphth(2,3-d)imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-Pralurbactam
go.drugbank.com/drugs/DB19437InvestigationalPralurbactam is under investigation in clinical trial NCT06633718 (Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAI).
Synonyms: 1R,2S,5R)-2-{[2-(guanidinooxy)ethoxy]carbamoyl}-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate, (1R,2S,5R)-2-[[[2-[[(Aminoiminomethyl)amino]oxy]ethoxy]amino]carbonyl]-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl hydrogen sulfateRocbrutinib
go.drugbank.com/drugs/DB19445InvestigationalRocbrutinib is under investigation in clinical trial NCT05716087 (A Study of Rocbrutinib in Participants With Relapse or Refractory Mantle Cell Lymphoma).
Synonyms: 2-Propenamide, N-[5-[[6-[2-(1,3,4,6,7,8-hexahydro-7,7-dimethyl-1-oxo-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)-3-(hydroxymethyl)-4-pyridinyl]-3,4-dihydro-4-methyl-3-oxo-2-pyrazinyl]amino]-2-[(2S)-2, N-[5-[[6-[2-(1,3,4,6,7,8-Hexahydro-7,7-dimethyl-1-oxo-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)-3-(hydroxymethyl)-4-pyridinyl]-3,4-dihydro-4-methyl-3-oxo-2-pyrazinyl]amino]-2-[(2S)-2-methyl-4-(tetrahydro