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Cerliponase alfa
go.drugbank.com/drugs/DB13173ApprovedInvestigational[L51339] It was also approved by the EMA on May 30, 2017 [L51324] and by Health Canada on December 19, 2018.
Olaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health Canada in April 2016.[L42820]
Methionine
go.drugbank.com/drugs/DB00134ApprovedInvestigationalNutraceuticalA sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Synonyms: MMixtures: Clinimix E, Clinimix ENM-3
go.drugbank.com/drugs/DB12818InvestigationalNM-3 has been used in trials studying the treatment of Neoplasms.
Synonyms: NM-3EI-1071
go.drugbank.com/drugs/DB18486InvestigationalEI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor.
Iberdomide
go.drugbank.com/drugs/DB12101Investigational[L64055] It binds cereblon, the substrate-recognition component of an E3 ubiquitin ligase complex, and drives the ubiquitination and proteasomal degradation of the transcription factors Aiolos and Ikaros … [L64055,L64056] It is the first cereblon E3 ligase modulator (CELMoD) approved for multiple myeloma.[L64057]
Categories: Cereblon E3 ligase modulatorSMART101
go.drugbank.com/drugs/DB18370InvestigationalSMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.
Mitemcinal
go.drugbank.com/drugs/DB06587InvestigationalMitemcinal (GM-611) is a novel erythromycin-derived prokinetic agent that acts as an agonist at the motilin receptor.
Fenretinide
go.drugbank.com/drugs/DB05076InvestigationalA synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Rosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigational[A181523] This last point results in less risk of drug-drug interactions compared to [atorvastatin], [lovastatin], and [simvastatin], which are all extensively metabolized by Cytochrome P450 (CYP) 3A4,
Mixtures: ROSUVINA LEGRAND® E 10/40, ROSUVINA LEGRAND® E 10/20Products: ROSUVASTATINA EG, M-rosuvastatin