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Displaying results 931 - 940 of 10000 in total
  1. Drug

    Febuxostat

    go.drugbank.com/drugs/DB04854
    ApprovedInvestigational

    Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. … [A230548] In February 2019, a black box warning for febuxostat was added, based on the findings of a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular

    Synonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acidCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  2. Drug

    Isoprenaline

    go.drugbank.com/drugs/DB01064
    ApprovedInvestigational

    [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than [adrenaline]. … Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion

    Synonyms: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol, 1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanolInternational brands: Proternol L
  3. Drug

    Prednisone

    go.drugbank.com/drugs/DB00635
    ApprovedInvestigationalVet approved

    A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver. … [L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]

    Categories: CHOP-R chemotherapy regimen, P-glycoprotein inducersSynonyms: 1, 2-Dehydrocortisone, 1,4-Pregnadiene-17α,21-diol-3,11,20-trione
  4. Drug

    Tigulixostat

    go.drugbank.com/drugs/DB18799
    Investigational

    Synonyms: 1h-pyrazole-4-carboxylic acid, 1-(3-cyano-1-(1-methylethyl)-1h-indol-5-yl)-
  5. Drug

    1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE

    go.drugbank.com/drugs/DB08590
    Experimental

    Synonyms: 1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE
  6. Drug

    4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide

    go.drugbank.com/drugs/DB08697
    Experimental

    Synonyms: 4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide
  7. Drug

    2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide

    go.drugbank.com/drugs/DB07984
    Experimental

    Synonyms: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide
  8. Drug

    Triclosan

    go.drugbank.com/drugs/DB08604
    Approved

    An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. … It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards

    Mixtures: PREVENT 2 EN 1, KURSEPT %19 + %1 KREM (30 G)Synonyms: 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol, 2,4,4'-Trichloro-2'-hydroxydiphenyl ether
  9. Drug

    7-methyl-guanosine-5'-triphosphate

    go.drugbank.com/drugs/DB02716
    Experimental

    Synonyms: 7-methyl-GTP(1+), 7-methyl-guanosine-5'-triphosphate
  10. Drug

    Clorazepic acid

    go.drugbank.com/drugs/DB00628
    ApprovedIllicit

    In September 2020, a black box warning describing these risks was included on the product label of benzodiazepines as per FDA regulation. … Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid