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DTx-1252
go.drugbank.com/drugs/DB18086ExperimentalDTx-1252 is a siRNA therapeutic under investigation for the treatment of Charcot-Marie-Tooth Disease type 1A (CMTD1A).[L48096]
PLG-0206
go.drugbank.com/drugs/DB18116InvestigationalPLG-0206 is a peptide antibiotic under investigation for the treatment of periprosthetic joint infections.[L48106]
OTOF-GT
go.drugbank.com/drugs/DB18129InvestigationalOTOF-GT is a dual vector AAV gene therapy being investigated for the restoration of hearing loss associated with otoferlin deficiency.
PBKR03
go.drugbank.com/drugs/DB18138InvestigationalPBKR03 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, containing a transgene encoding the human galactosylceramidase (GALC) enzyme.
TN-401
go.drugbank.com/drugs/DB18140InvestigationalTN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Synonyms: A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 geneEfocipegtrutide
go.drugbank.com/drugs/DB18194InvestigationalEfocipegtrutide is a long-acting, monomeric peptide triple agonist.
XMT-2056
go.drugbank.com/drugs/DB18230InvestigationalXMT-2056 is a HER2-targeted antibody-drug conjugate (ADC) consisting of a HER2-targeted antibody conjugated with a stimulator of interferon genes (STING) agonist payload.
AP103
go.drugbank.com/drugs/DB18234ExperimentalAP103 is a non-viral gene therapy that uses a delivery vector, HPAE (Highly Branched Poly β-Amino Ester), to deliver the correct collagen VII gene into skin cells.
DCN-tCRK
go.drugbank.com/drugs/DB18262ExperimentalDCN-tCRK is a recombinant, multi-functional fusion protein consisting of human decorin fused to the C-terminal vascular homing peptide tCRK.
HM15912
go.drugbank.com/drugs/DB18266InvestigationalHM15912 is a human glucagon-like peptide-2 analogue linked to a human immunoglobulin Fc fragment.