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Crizotinib
go.drugbank.com/drugs/DB08865ApprovedInvestigationalCrizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic … [L42460] By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers robust effectiveness in treating NSCLC in patients with this type of rearrangement
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (R)-crizotinibBrentuximab vedotin
go.drugbank.com/drugs/DB08870ApprovedInvestigational[L1737] The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy regimen compared to the previous standard of care. … Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE).
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ADCETRIS®, ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADETFidaxomicin
go.drugbank.com/drugs/DB08874ApprovedInvestigationalFidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and pediatric patients over the age of 6 months. … [L11575] Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: Tiacumicin BTaliglucerase alfa
go.drugbank.com/drugs/DB08876ApprovedTaliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. … It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Synonyms: prGC-DProducts: ELELYSO 200 U İNFÜZYONLUK SOLÜSYON İÇİN LİYOFİLİZE TOZ, 1 ADET4-methyl-umbelliferyl-N-acetyl-chitobiose
go.drugbank.com/drugs/DB02759ExperimentalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 4-methylumbelliferyl-N,N-diacetylchitobioside, 4-methyl-umbelliferyl-N-acetyl-chitobioseA-98881
go.drugbank.com/drugs/DB02804ExperimentalCategories: Heterocyclic Compounds, 1-RingSynonyms: A-98881Siroheme
go.drugbank.com/drugs/DB02832ExperimentalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsS-Adenosyl-1,8-Diamino-3-Thiooctane
go.drugbank.com/drugs/DB02844ExperimentalCategories: Heterocyclic Compounds, 2-RingSynonyms: S-Adenosyl-1,8-Diamino-3-ThiooctaneDeacetoxyvinzolidine
go.drugbank.com/drugs/DB02868ExperimentalCategories: Heterocyclic Compounds, 2-RingRhamnose
go.drugbank.com/drugs/DB02961InvestigationalA methylpentose whose L- isomer is found naturally in many plant glycosides and some gram-negative bacterial lipopolysaccharides. [PubChem]
Synonyms: L-rhamnose