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Atorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigationalAtorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. … the number of major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.
Mixtures: ./5 มก./5 มก., TIAZOMET ® A 40/10 TABLETASCategories: P-glycoprotein inhibitors, P-glycoprotein substratesCiltacabtagene autoleucel
go.drugbank.com/drugs/DB16738ApprovedInvestigational[L40749] There have been a number of treatments developed for multiple myeloma (e.g. [daratumumab]), although none are curative. … [L40739] Patient T-cells are reprogrammed with a transgene encoding a specific chimeric antigen receptor (CAR) which features two BCMA-targeting single-domain antibodies.
Synonyms: Autologous bi-epitope BCMA-targeted CAR T-cellsCategories: Antineoplastic cell and gene therapyLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Synonyms: N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingCalcipotriol
go.drugbank.com/drugs/DB02300ApprovedInvestigationalCalcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Mixtures: Daivobet Gel 50mcg/g + 0.5mg/g, DAIVOBET® GEL 50 MCG + 0.5 MG/ GCategories: Vitamin D and AnaloguesGlycyrrhizic acid
go.drugbank.com/drugs/DB13751ApprovedInvestigational[T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of chronic hepatitis. … [F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities.
Lovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigationalwere found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40%. … [A181087,A181553] Use of statins to target and reduce LDL levels has been shown in a number of landmark studies to significantly reduce the risk of development of CVD and all-cause mortality.
Synonyms: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate, 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactoneCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsTriamterene
go.drugbank.com/drugs/DB00384ApprovedTriamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension. … Triamterene is a weak antagonist of folic acid, and a photosensitizing drug.[L6163] Triamterene was approved by the Food and Drug Administration in the U.S. in 1964.
Synonyms: 6-phenylpteridine-2,4,7-triamineMixtures: DYTIDE H, DYTIDE HOctocrylene
go.drugbank.com/drugs/DB09535ApprovedBecause of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than … Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties.
Mixtures: Derma Geek Nourishing Facial Moisturizer with Sunscreen Broad Spectrum SPF 30, City Sunscreen Serum SPF 30 Doctor Ts Super goopProducts: Panama Jack SPF 4, Panama Jack SPF 4 Dark Tanning OilOsilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigationalhas not been curative. … Cushing's disease is often the result of ACTH hypersecretion secondary to a pituitary tumor, and surgical resection of the tumour is generally the treatment of choice.
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesCiclesonide
go.drugbank.com/drugs/DB01410ApprovedInvestigationalCiclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Mixtures: LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL,120 KAPSÜL, LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇIEREN KAPSÜL,60 KAPSÜLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates