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Displaying results 941 - 950 of 10000 in total
  1. Drug

    Zidovudine monophosphate

    go.drugbank.com/drugs/DB03666
    Experimental

    Synonyms: 3'-Azido-2',3'-deoxythymidine 5'-monophosphate, 3'-Azido-3'-deoxythymidine 5'-phosphateCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488] … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.

    Synonyms: (2R)-2-acetylamino-3-sulfanylpropanoic acid, (R)-2-acetylamino-3-mercaptopropanoic acidMixtures: AMINOPLASMAL-5% E INFUSION, AMINOPLASMAL-10% E INFUSION
  3. Drug

    Lenacapavir

    go.drugbank.com/drugs/DB15673
    ApprovedInvestigational

    [L42995] On December 22, 2022, it was also approved by the FDA.[L44473] … [A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral

    Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: -3-(TRIFLUOROMETHYL)-3B,4,4A,5-TETRAHYDRO-1H-CYCLOPR, N-((1S)-1-(3-(4-CHLORO-3-(METHANESULFONAMIDO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-(METHANESULFONYL)-3-METHYLBUT-1-YN-1-YL)PYRIDIN-2-YL)-2-(3,5- DIFLUOROPHENYL)ETHYL)-2-((3BS,4AR)-5,5-DIFLUORO
  4. Drug

    Stiripentol

    go.drugbank.com/drugs/DB09118
    ApprovedInvestigational

    [L880,L42500,L42510] It is marketed under the brand name Diacomit. … Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP1A2 InducersSynonyms: 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol, 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol
  5. Drug

    Emrusolmin

    go.drugbank.com/drugs/DB13927
    Investigational

    Emrusolmin restores hippocampal synaptic and transcriptional plasticity as well as spatial memory in a mouse model for Alzheimer's disease, when given orally before or after the onset of pathology.

    Synonyms: 1H-PYRAZOLE, 3-(1,3-BENZODIOXOL-5-YL)-5-(3-BROMOPHENYL)-, 3-(1,3-BENZODIOXOL-5-YL)-5-(3-BROMOPHENYL)-1H-PYRAZOLECategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    CPZEN-45

    go.drugbank.com/drugs/DB18077
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-{[(5-amino-3,3-dihydroxyoxolan-2-yl)oxy][5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl}-N-(4-butylphenyl)-4,7-dimethyl-6-oxocyclohept-1-ene-1-carboxamide, Uridine, 5'-o-(5-amino-5-deoxy-.beta.-d-ribofuranosyl)-5'-c-((2s)-5-(((4-butylphenyl)amino)carbonyl)-2,3,4,7-tetrahydro-1,4-dimethyl-3-oxo-1h-1,4-diazepin-2-yl)-, (5's)-
  7. Drug

    Fluorometholone

    go.drugbank.com/drugs/DB00324
    ApprovedInvestigational

    A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)

    Mixtures: EFEMOLINE 5 ML DAMLA, FLU-SURE T® SUSPENSIÓN OFTÁLMICACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  8. Drug

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid

    go.drugbank.com/drugs/DB16029
    Investigational

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).

    Synonyms: 2-(5-fluoro-pentyl)-2-methyl-malonic-acid
  9. Drug

    Streptomycin

    go.drugbank.com/drugs/DB01082
    ApprovedInvestigationalVet approved

    [A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as

    Synonyms: 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranosideCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  10. Drug

    Bucladesine

    go.drugbank.com/drugs/DB13242
    Experimental

    Synonyms: 3',5'-cyclic AMP dibutyrate, dibutyryl-3',5'-AMPCategories: Heterocyclic Compounds, 2-Ring