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Displaying results 9571 - 9580 of 10000 in total
  1. Drug

    ZK-93423

    go.drugbank.com/drugs/DB17063
    Experimental

    ZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.[A253172]

    Synonyms: 9H-Pyrido[3,4-b]indole-3-carboxylicacid, 4-(methoxymethyl)-6-(phenylmethoxy)-, ethyl esterCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    ZM-39923

    go.drugbank.com/drugs/DB17064
    Experimental

    ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).[A253177]

    Synonyms: 1-propanone, 3-((1-methylethyl)(phenylmethyl)amino)-1-(2-naphthalenyl)-, 3-(benzyl(propan-2-yl)amino)-1-(naphthalen-2-yl)propan-1-one
  3. Drug

    Autologous Hematopoietic Peripheral Blood Stem Cells

    go.drugbank.com/drugs/DB17067
    Investigational

    Autologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.

  4. Drug

    αAβ–Gas6

    go.drugbank.com/drugs/DB17069
    Experimental

    It is made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is a ligand … αAβ–Gas6 is a chimeric fusion protein being investigated in preclinical studies as an immunotherapeutic agent for Alzheimer's disease (AD).

  5. Drug

    Tabelecleucel

    go.drugbank.com/drugs/DB17072
    ApprovedInvestigational

    When given to a patient with EBV-associated post-transplant lymphoproliferative disorder (PTLD) following solid organ transplantation (SOT) or hematopoietic cell transplant, T-cells attack the patient's … Both T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers.

  6. Drug

    AZD2066

    go.drugbank.com/drugs/DB17078
    Investigational

    Synonyms: Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)-Categories: Heterocyclic Compounds, 1-Ring, Receptor, Metabotropic Glutamate 5, antagonists & inhibitors
  7. Drug

    Linzagolix

    go.drugbank.com/drugs/DB17083
    ApprovedInvestigational

    Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. … [A253662] As these fibroids are essentially estrogen-dependent phenomena, hormone therapies which suppress estrogen activity - including GnRH receptor antagonists like linzagolix - are thought to be beneficial

    Synonyms: 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno(3,4-d)pyrimidine-5-carboxylic acid, Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-1,2,3,4-tetrahydro-2,4-dioxo-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
  8. Drug

    Norclobazam

    go.drugbank.com/drugs/DB17092
    Investigational

    Synonyms: 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 8-chloro-1-phenyl-7-chloro-5-phenyl-1,2,4,5-tetrahydro-3h-1,5-benzodiazepine-2,4-dione, N-desmethylclobazamCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  9. Drug

    NEO-212

    go.drugbank.com/drugs/DB17100
    Investigational

    Synonyms: Carbamic acid, n-((3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazin-8-yl)carbonyl)-, ((4s)-4-(1-methylethenyl)-1-cyclohexen-1-yl)methyl ester, (s)-perillyl alcohol temozolomide carbamateCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    SC 41930

    go.drugbank.com/drugs/DB17101
    Experimental

    Synonyms: (+/-)-7-(3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy)-3,4-dihydro-8-propyl-2h-1-benzopyran-2-carboxylic acid, 2h-1-benzopyran-2-carboxylic acid, 7-(3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy)-3,4-dihydro-8-propyl-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring