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Displaying results 951 - 960 of 10000 in total
  1. Drug

    TD-0903

    go.drugbank.com/drugs/DB16463
    Investigational

    TD-0903 was investigated in clinical trials for its potential to treat acute lung injury (ALI) associated with COVID-19, including NCT04350736, NCT05091723 (a pharmacokinetics study in healthy participants

    Synonyms: (3-(DIMETHYLAMINO)AZETIDIN-1-YL)((6S)-2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-5-(PROPAN-2-YL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZO(4,5-C)PYRIDIN-6-YL)METHANONE, (S)-(3-(DIMETHYLAMINO)AZETIDIN-1-YL)(2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-5-ISOPROPYL-4,5,6,7-TETRAHYDRO-3H-IMIDAZO(4,5-C)PYRIDIN-6-YL)METHANONECategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Rimtuzalcap

    go.drugbank.com/drugs/DB16733
    Investigational

    Rimtuzalcap is a novel modulator of small-conductance calcium-activated potassium channels that is under investigation for the treatment of essential tremor.[L38414]

    Synonyms: N-(4,4-difluorocyclohexyl)-2-(3-methyl-1H-pyrazol-1-yl)-6-morpholinopyrimidin-4-amine
  3. Drug

    Procinonide

    go.drugbank.com/drugs/DB18737
    ApprovedWithdrawn

    Synonyms: Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-21-(1-oxopropoxy)-, (6.alpha.,11.beta.,16.alpha)-, 6.alpha.,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-propionate
  4. Drug

    Tideglusib

    go.drugbank.com/drugs/DB12129
    ApprovedInvestigationalWithdrawn

    It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3).

    Synonyms: 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE, 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dioneCategories: Heterocyclic Compounds, 1-Ring, Glycogen Synthase Kinase 3, antagonists & inhibitors
  5. Drug

    Thenalidine

    go.drugbank.com/drugs/DB04826
    ApprovedWithdrawn

    Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.

    Synonyms: 1-Methyl-4-N-2-thenylanilinopiperidine, 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidineCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Glycerol phenylbutyrate

    go.drugbank.com/drugs/DB08909
    ApprovedInvestigational

    Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.

    Synonyms: Glyceryl Tri-4-PhenylbutyrateCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2D6 Inhibitors
  7. Drug

    Benorilate

    go.drugbank.com/drugs/DB13657
    Approved

    Synonyms: 4-acetamidophenyl salicylate acetateCategories: Non COX-2 selective NSAIDS
  8. Drug

    Idrevloride

    go.drugbank.com/drugs/DB18042
    Experimental

    Synonyms: 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl((2S,3R,4R, 5R)-2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)-carbamimidoyl)pyrazine-2-carboxamide, D-glucitol, 1-deoxy-1-((2-(4-(4-(((((3,5-diamino-6-chloro-2-pyrazinyl)carbonyl)amino)iminomethyl)amino)butyl)phenoxy)ethyl)hexylamino)-
  9. Drug

    Osivelotor

    go.drugbank.com/drugs/DB18071
    Investigational

    Synonyms: (S)-2-hydroxy-6-((4-(2-(2-hydroxyethyl)nicotinoyl)morpholin- 3-yl)methoxy)benzaldehyde
  10. Drug

    3-(4-Fluorophenyl)-2-(6-Methylpyridin-2-Yl)-5,6-Dihydro-4h-Pyrrolo[1,2-B]Pyrazole

    go.drugbank.com/drugs/DB04480
    Experimental

    Synonyms: 3-(4-Fluorophenyl)-2-(6-Methylpyridin-2-Yl)-5,6-Dihydro-4h-Pyrrolo[1,2-B]Pyrazole