Thenalidine

DB04826ApprovedWithdrawnSmall molecule

Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.

Chemical structure of Thenalidine
Mechanism
Curator reviewed
Formula / weight
C17H22N2S · 286.435 g/mol (avg)
Also known as
Thenophenopiperidine
Code names
AS 716

Resolves to

Compound
UNII6U94N2D00FCAS86-12-4ChEMBLCHEMBL2105458ChEBI135187PubChem27901
Clinical / RWD
ATCD04AA03ATCR06AX03ATCR06AX53
Structure
InChIKeyKLOHYVOVXOUKQI-UHFFFAOYSA-NSMILESCN1CCC(CC1)N(CC1=CC=CS1)C1=CC=CC=C1
Targets
P35367HRH1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
9Drug interactionsStructured to mechanism, not free text
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3ATC codesIncluding every combination product, plus 4 drug categories
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Thenalidine, and which of those have an active Phase 3 trial?

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