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Teclistamab
go.drugbank.com/drugs/DB16655ApprovedInvestigational[A253587] Teclistamab consists of an anti-BCMA arm and an anti-CD3 arm connected via two interchain disulfide bonds,[A253587, L43622] allowing the drug to recruit CD3-expressing T cells to BCMA-expressing … Teclistamab is an IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells.
Categories: Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engagerDarvadstrocel
go.drugbank.com/drugs/DB16581ApprovedInvestigationalWithdrawnPerianal fistula is a common manifestation of Crohn’s disease and is often difficult to manage, as it may be associated with complex presentations and symptoms. … It is indicated for the treatment of complex perianal fistulas in adult patients with non-active or mildly active luminal Crohn’s disease when fistulas have shown an inadequate response to at least one
Baloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET, XOFLUZA 20 MG FİLM KAPLI TABLET, 4 ADETTrifluridine
go.drugbank.com/drugs/DB00432ApprovedInvestigationalanti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy. … It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus.
Categories: Heterocyclic Compounds, 1-RingSynonyms: F₃T, 5-Trifluoromethyl-2-deoxyuridineFelbamate
go.drugbank.com/drugs/DB00949ApprovedFelbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). … It has a weak inhibitory effect on GABA receptor binding sites.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester, 2-phenyl-1,3-propanediol dicarbamateEstradiol cypionate
go.drugbank.com/drugs/DB13954ApprovedVet approved[DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%). … Estradiol cypionate is commercially available as Depo-Estradiol, an intramuscular depot injection used for the treatment of moderate to severe vasomotor symptoms associated with menopause and for the treatment
Mixtures: FEMELIN®, FEMELIN®Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesMifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalAlso called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). … Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes.
Products: MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET, MEPACT® POLVO PARA CONCENTRADO PARA DISPERSIÓN PARA PERFUSIÓNCoagulation Factor IX Human
go.drugbank.com/drugs/DB13152ApprovedInvestigationalDeficiency of this protein causes hemophilia B.
Synonyms: Antihemophilic factor BMixtures: UMAN COMPLEX, UMAN COMPLEXDipotassium phosphate
go.drugbank.com/drugs/DB09414ApprovedInvestigationalDipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Synonyms: Phosphoric acid, potassium salt (1:2)Mixtures: INYECCION DE FOSFATO DE POTASIO, INYECCION DE FOSFATO DE POTASIOMethsuximide
go.drugbank.com/drugs/DB05246ApprovedMesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: N,2-Dimethyl-2-phenylsuccinimide, 1,3-Dimethyl-3-phenylsuccinimide