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Displaying results 951 - 960 of 7283 in total
  1. Drug

    Cefiderocol

    go.drugbank.com/drugs/DB14879
    ApprovedInvestigational

    eradication with cefiderocol compared to 54.6% with the comparator, imipenem/cilastatin. … Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam antibiotics.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Triethylenetetramine

    go.drugbank.com/drugs/DB06824
    ApprovedInvestigational

    Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. … [A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and

    Categories: Compounds used in a research, industrial, or household setting, Copper Chelator
  3. Drug

    Polymyxin B

    go.drugbank.com/drugs/DB00781
    ApprovedInvestigationalVet approved

    Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label].

    Mixtures: Dr Bells Pomade, Pomada De La Campana Triple Antibiotic Pain Relief
  4. Drug

    Ammonium chloride

    go.drugbank.com/drugs/DB06767
    ApprovedInvestigationalVet approved

    Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.

    Mixtures: DM Syrup, DONEXAN DX
  5. Drug

    Heparin

    go.drugbank.com/drugs/DB01109
    ApprovedInvestigational

    Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. … It is a naturally occurring anticoagulant released from mast cells.

    Mixtures: "Aponova" Heparin comp. - GelProducts: HEPARIN NA BRA 25000IE, HEPARIN NA BRA 25000IE IIL
  6. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    The FDA first approved Hydrocodone for use as part of the cough suppressant syrup Hycodan in March of 1943.[L9025] … Hydrocodone is a synthetic opioid derivative of codeine.[T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain.

    Mixtures: Novahistex Dh, Vasofrinic Dh
  7. Drug

    Gemfibrozil

    go.drugbank.com/drugs/DB01241
    ApprovedInvestigational

    [L8525] Gemfibrozil was granted FDA approval on 21 December 1981.[L8525] … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias.

  8. Drug

    Isavuconazole

    go.drugbank.com/drugs/DB11633
    ApprovedInvestigational

    Resistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label]. … Cross-resistance between isavuconazole and other azoles was also proposed although the clinical relevance is unclear [FDA Label].

  9. Drug

    Technetium Tc-99m tilmanocept

    go.drugbank.com/drugs/DB09266
    Approved

    It is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose, each covalently attached to a 10 kDa dextran backbone [FDA Label]. … DTPA serves as a chelating agent for technetium Tc 99m to bind [FDA Label].

  10. Drug

    Meradimate

    go.drugbank.com/drugs/DB11096
    Approved

    Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. … [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.

    Mixtures: Clinic A Retinol Vital Day Moist Lot Spf20, Herbal Day Creme SPF 15