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NTLA-2001
go.drugbank.com/drugs/DB18525InvestigationalNTLA-2001 is a clustered regularly interspaced short palindromic repeats CRISPR/ Cas9-based gene therapy consisting of a single guide RNA targeting the human TTR gene and a messenger RNA encoding Cas9.
DCVAC/OvCa
go.drugbank.com/drugs/DB18571InvestigationalIt is under investigation for the treatment of ovarian cancer.
Otamixaban
go.drugbank.com/drugs/DB06635InvestigationalIt is currently being developed by the French pharmaceutical company Sanofi-Aventis as a treatment for acute coronary syndrome.
3,3'-diindolylmethane
go.drugbank.com/drugs/DB11875InvestigationalDiindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.
Exebacase
go.drugbank.com/drugs/DB16161InvestigationalPlacebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).
Fenpyroximate
go.drugbank.com/drugs/DB16164InvestigationalFenpyroximate is under investigation in clinical trial NCT02533336 (The Effectiveness of Non-pyrethroid Insecticide-treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania
Synonyms: Fenpyroximate (z,e)ASP-8731
go.drugbank.com/drugs/DB17696InvestigationalDeveloped by Mitobridge, it is being investigated for the treatment of sickle cell disease.[L46093]
Bacteroides thetaiotaomicron
go.drugbank.com/drugs/DB17879InvestigationalDeveloped by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.[A259892]
CYNK-101
go.drugbank.com/drugs/DB18637InvestigationalCYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Synonyms: allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP)Famitinib
go.drugbank.com/drugs/DB11741InvestigationalFamitinib has been used in trials studying the treatment of Colorectal Cancer, Renal Cell Cancer, Colorectal Cancer Recurrent, Colorectal Cancer Metastatic, and Metastatic Renal Cell Cancer, among others
Categories: Receptor Protein-Tyrosine Kinases, antagonists & inhibitors