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V-SARS
go.drugbank.com/drugs/DB15812InvestigationalImmunitor Inc., the sponsor, is currently testing this oral vaccine for immunogenicity in 20 healthy volunteers in a Phase 1 clinical trial (NCT04380532).
IMMU-114
go.drugbank.com/drugs/DB18458InvestigationalIMMU-114 is antibody-drug conjugate consisting of humanized anti-HLA-DR IgG4 monoclonal antibody specific for alpha-chain linked to SN-38 via a CL2A linker.
ALT-P1
go.drugbank.com/drugs/DB18485InvestigationalALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Reloxiliase
go.drugbank.com/drugs/DB17653ExperimentalReloxiliase is a first-in-class, oral crystalline formulation of the oxalate-specific, microbial enzyme oxalate decarboxylase. It is being investigated for the treatment of hyperoxaluria.[A258823]
WP-1301
go.drugbank.com/drugs/DB17702ExperimentalIt binds to an MHC class II molecule and is recognized by a Factor VIII-specific T cell.[L46138]
NOP-1A
go.drugbank.com/drugs/DB15208InvestigationalNOP-1A is under investigation in clinical trial NCT01198197 (PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A).
GLPG-1205
go.drugbank.com/drugs/DB15346InvestigationalGLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective and Safe GLPG1205 is for Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Sofituzumab vedotin
go.drugbank.com/drugs/DB15349InvestigationalSofituzumab vedotin is under investigation in clinical trial NCT01335958 (Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable
Timbetasin
go.drugbank.com/drugs/DB19119InvestigationalTimbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Synonyms: L-SERINE, N-ACETYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-LYSYL-L-PROLYL-L-.ALPHA.-ASPARTYL-L-METHIONYL-L-ALANYL-L-.ALPHA.-GLUTAMYL-L-ISOLEUCYL-L-.ALPHA.-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-.ALPHA., N-ACETYL-L-SERYL-L-ASPARTYL-L-LYSYL-L-PROLYL-L-ASPARTYL-L-METHIONYL-L-ALANYL-L-GLUTAMYL-L-ISOLEUCYL-L-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-ASPARTYL-L-LYSYL-L-SERYL-L-LYSYL-L-LEUCYL-L-LYSYL-L-LYSYL-L-THEONYL-L-GLUTAMYL-L-THEONYL-L-GLUTAMINYL-L-GLUTAMYL-L-LYSAZD-4017
go.drugbank.com/drugs/DB14875InvestigationalAZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).