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Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)-
go.drugbank.com/drugs/DB16204Investigationalthe Reduction of Inflammation in Patients With Active Rheumatoid Arthritis). … Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)- is under investigation in clinical trial NCT00545454 (Activity and Safety of Oral Administration of SSR150106XB for
ARCoV
go.drugbank.com/drugs/DB15855ExperimentalIt is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd. and the People’s Liberation Army (PLA) Academy … Preclinical studies in mice and non-human primates has shown that intramuscular administration of ARCoV elicited a Th1-biased cellular response and robust antibodies against SARS-CoV-2[A220048].
Etiracetam
go.drugbank.com/drugs/DB11868ExperimentalEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
BNT111
go.drugbank.com/drugs/DB18177InvestigationalBNT111 is an investigational cancer immunotherapy under development for advanced melanoma. It consists of a fixed combination of mRNA-encoded, tumor-associated antigens.
BMS-955176
go.drugbank.com/drugs/DB15193InvestigationalBMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults).
Udifitimod
go.drugbank.com/drugs/DB19053InvestigationalUdifitimod is under investigation in clinical trial NCT05014438 (A Study of BMS-986166 or Branebrutinib for the Treatment of Participants With Atopic Dermatitis).
OTX-2002
go.drugbank.com/drugs/DB17246InvestigationalOTX-2002 is a bicistronic messenger ribonucleic acid (mRNA) encoding for ZF-DNMT and ZF-KRAB proteins, encapsulated in a lipid nanoparticle (LNP).
Filaminast
go.drugbank.com/drugs/DB02660ExperimentalFilaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). As such, has potential in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Gam-COVID-Vac
go.drugbank.com/drugs/DB15848InvestigationalJune 2020, and were completed in early August 2020. … The vaccine is offered in both a frozen (Gam-COVID-Vac) and freeze-dried formulation (lyophilizate; Gam-COVID-Vac Lyo).
Englumafusp alfa
go.drugbank.com/drugs/DB19341InvestigationalEnglumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab … and in Combination With Glofitamab Following a Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/refractory B-cell Non-hodgkin's Lymphoma).