Englumafusp alfa

DB19341InvestigationalProtein Based Therapies

Englumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination...

Mechanism
Curator reviewed
Also known as
71-248-4-1BB ligand (human precursor) fusion protein with peptide linker (GGGGS)2 fusion protein with 71-248-4-1BB ligand (human precursor) peptide linker (GGGGS)2 fusion protein with human κ-chain C region fusion protein with immunoglobulin G1 [497-ala · Ensomafusp alfa · humanized immunoglobulin G1-kappa anti-(human B-lymphocyte antigen CD19) modified heterodimer where the heavy and light chain variable regions of one arm have been substituted by three subunits of human 4- 1BB ligand (tumor necrosis factor ligand superfa
Code names
RG6076 · RO-7227166

Resolves to

What you can answer from here — as of July 09, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Englumafusp alfa, and which of those have an active Phase 3 trial?

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