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Displaying results 9671 - 9680 of 10000 in total
  1. Drug

    Phosphoaminophosphonic Acid-Adenylate Ester

    go.drugbank.com/drugs/DB04395
    Experimental

    An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. … It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]

  2. Drug

    SYNB1891

    go.drugbank.com/drugs/DB17541
    Investigational

    SYNB1891 is a live, modified strain of the probiotic _Escherichia coli_ Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway. … [A256733] SYNB1891 is under investigation in clinical trial NCT04167137 (Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult Subjects).

  3. Drug

    9-(4-hydroxybutyl)-N2-phenylguanine

    go.drugbank.com/drugs/DB02495
    Experimental

    9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. … These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase.

  4. Drug

    EGT-201

    go.drugbank.com/drugs/DB17648
    Experimental

    Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type B.[L45939] … EGT-201 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the alpha-N-acetyglucosaminidase (NAGLU) transgene.

  5. Drug

    Arlocabtagene autoleucel

    go.drugbank.com/drugs/DB24024
    Investigational

    Arlocabtagene Autoleucel is a biologic drug. … Arlocabtagene Autoleucel is under investigation in clinical trial NCT06297226 (Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or

  6. Drug

    BPR001-615

    go.drugbank.com/drugs/DB33938
    Experimental

    BPR001-615 is a small molecule drug. … BPR001-615 is under investigation in clinical trial NCT07813884 (Exploratory Evaluation of the BiP Inhibitor BPR001-615 in Primary Cells and the Diagnostic Value of Circulating BiP in Colorectal Adenocarcinomas

  7. Drug

    AD-233C

    go.drugbank.com/drugs/DB33954
    Experimental

    AD-233C is a small molecule drug. … AD-233C is under investigation in clinical trial NCT07816198 (A Study to Evaluate the Efficacy and Safety of AD-233A, AD-233B, AD-233C and/or AD-233D Combination Therapy).

  8. Drug

    AD-233D

    go.drugbank.com/drugs/DB33955
    Experimental

    AD-233D is a small molecule drug. … AD-233D is under investigation in clinical trial NCT07816198 (A Study to Evaluate the Efficacy and Safety of AD-233A, AD-233B, AD-233C and/or AD-233D Combination Therapy).

  9. Drug

    AD-233A

    go.drugbank.com/drugs/DB33952
    Experimental

    AD-233A is a small molecule drug. … AD-233A is under investigation in clinical trial NCT07816198 (A Study to Evaluate the Efficacy and Safety of AD-233A, AD-233B, AD-233C and/or AD-233D Combination Therapy).

  10. Drug

    Florbenazine F-18

    go.drugbank.com/drugs/DB14945
    Investigational

    Florbenazine F-18 is under investigation in clinical trial NCT01515384 (A Trial of 18F-AV-133 Positron Emission Tomography (PET)).