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Isoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than [adrenaline].
Elafibranor
go.drugbank.com/drugs/DB05187ApprovedInvestigational[L50773] The drug was also approved by the EMA on September 23, 2024.[L51878] … [L50768] On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Fexinidazole
go.drugbank.com/drugs/DB12265Approved[A237555, L35940] It is currently marketed by Sanofi-Aventis.[L35940] … all-oral treatment for first and second stage HAT caused by _T. brucei gambiense_.
Categories: MATE 2-K InhibitorsBenzoic acid
go.drugbank.com/drugs/DB03793ApprovedInvestigationalAs the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. … Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo.
Sutimlimab
go.drugbank.com/drugs/DB14996ApprovedInvestigational[L40114,A245144] Sutimlimab was also approved by the European Commission in November 2022.[L44116] … [A245144] Hemolysis in patients with CAD is driven by complement activation, which initiates a cascade that ultimately leads to both intra- and extravascular hemolysis.
Encainide
go.drugbank.com/drugs/DB01228ApprovedWithdrawnThe manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Tigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalTigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. … It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Imolamine
go.drugbank.com/drugs/DB09284InvestigationalIt is developed under the brand name Coremax by Novartis consumer health SA.
Hepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigationalagainst the disease caused by infection with this virus. … [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]
Products: AVAXIM 80 U PEDIATRIC, VAQTA VACCINE 25 u/0.5 mlArdeparin
go.drugbank.com/drugs/DB00407ApprovedWithdrawnNormiflo was withdrawn from the US market in March 2000. … Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis.