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Rebeccamycin
go.drugbank.com/drugs/DB14729InvestigationalRebeccamycin is a weak topoisomerase I inhibitor isolated from _Nocardia sp_.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-RingPeginterferon lambda-1a
go.drugbank.com/drugs/DB14767InvestigationalPeginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).
DCFBC F-18
go.drugbank.com/drugs/DB14772InvestigationalDCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Synonyms: DCFBC F-18Lifirafenib
go.drugbank.com/drugs/DB14773InvestigationalLifirafenib is under investigation in clinical trial NCT03641586 (The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor).
Categories: Heterocyclic Compounds, 2-RingLGD-6972
go.drugbank.com/drugs/DB14779InvestigationalLGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes
Vofatamab
go.drugbank.com/drugs/DB14781InvestigationalVofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma).
Tofersen
go.drugbank.com/drugs/DB14782ApprovedInvestigational[L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented. … [L46133] Continual FDA approval is contingent on clinical benefits from ongoing trials, particularly the Phase 3 ATLAST study in people with presymptomatic SOD1-ALS.
Synonyms: DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP, -(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RDiroximel fumarate
go.drugbank.com/drugs/DB14783ApprovedInvestigational[A187535] Diroximel fumarate is a new drug from the fumarate class formulated to treat various relapsing forms of MS. … Multiple Sclerosis (MS) is a chronic, debilitating neurological disease that can lead to profound cognitive and physical symptoms, severely affecting quality of life.
Fenebrutinib
go.drugbank.com/drugs/DB14785InvestigationalFenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin).
Categories: Heterocyclic Compounds, 1-Ring