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Displaying results 9721 - 9730 of 10000 in total
  1. Drug

    PF-04634817

    go.drugbank.com/drugs/DB14955
    Investigational

    PF-04634817 is under investigation in clinical trial NCT01140672 (A Multiple Dose Study To Determine Safety, Tolerability, and Pharmacokinetics Of PF-04634817 In Healthy Adult Subjects).

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Selicrelumab

    go.drugbank.com/drugs/DB14958
    Investigational

    Selicrelumab is under investigation in clinical trial NCT01008527 (Phase I Oncovir Poly IC:LC and NY-ESO-1/gp100).

  3. Drug

    Seltorexant

    go.drugbank.com/drugs/DB14961
    Investigational

    Seltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Trastuzumab deruxtecan

    go.drugbank.com/drugs/DB14962
    ApprovedInvestigational

    Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers.

    Synonyms: T-DXd, T- DXdCategories: MATE 2 Substrates, P-glycoprotein substrates
  5. Drug

    Narnatumab

    go.drugbank.com/drugs/DB14964
    Investigational

    Narnatumab is under investigation in clinical trial NCT01119456 (A Study of IMC-RON8 in Advanced Solid Tumors).

  6. Drug

    Iomazenil

    go.drugbank.com/drugs/DB14971
    Investigational

    Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans).

    Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Methamidophos

    go.drugbank.com/drugs/DB14972
    Experimental

    Methamidophos is under investigation in clinical trial NCT03223753 (Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia in First Remission).

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Pimodivir

    go.drugbank.com/drugs/DB14974
    Investigational

    Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Voxelotor

    go.drugbank.com/drugs/DB14975
    Approved

    Voxelotor is a novel hemoglobin S polymerization inhibitor for the treatment of sickle cell disease. … This is a genetically inherited condition most prevalent in the Middle East, Africa, and certain parts of India.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  10. Drug

    Miransertib

    go.drugbank.com/drugs/DB14982
    Investigational

    Miransertib is under investigation in clinical trial NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma).

    Synonyms: 3-{3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}pyridin-2-amineCategories: Heterocyclic Compounds, 1-Ring