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MK-4965
go.drugbank.com/drugs/DB08460ExperimentalMK-4965 is an HIV-1 reverse transcriptase inhibitor.
PD-168393
go.drugbank.com/drugs/DB07662ExperimentalPD-168393 is an epidermal growth factor receptor inhibitor.
PF-04995274
go.drugbank.com/drugs/DB12675InvestigationalPf 04995274 is under investigation in clinical trial NCT01193062 (Study In Healthy Subjects To Evaluate The Changes In The Protein sAPP-Alpha In Cerebrospinal Fluid Following A Single Oral Dose Of PF-04995274
Simurosertib
go.drugbank.com/drugs/DB16330InvestigationalSimurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal
Synonyms: 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-oneBMS-986104
go.drugbank.com/drugs/DB15214Investigationalof BMS-986104 in Healthy Male Subjects). … BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
SD118
go.drugbank.com/drugs/DB05207ExperimentalSD118 was previously under investigation in Japan for a different indication and now, following re-profiling and evaluation in experimental animal models, has demonstrated its potential as a new oral therapy
PRO-1562
go.drugbank.com/drugs/DB33979ExperimentalPRO-1562 is under investigation in clinical trial NCT07826689 (A Phase 1/2a Study of Oral PRO-1562 in Healthy Subjects and Patients With Relapsing Multiple Sclerosis).
Enristomig
go.drugbank.com/drugs/DB29060InvestigationalINBRX-105 is under investigation in clinical trial NCT03809624 (Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer).
Ivarmacitinib
go.drugbank.com/drugs/DB16756InvestigationalWhile ivarmactinib has yet to receive marketing authorization, as of February 2022 clinical trials are ongoing or completed evaluating its use in atopic dermatitis,[L40604,L40619,L40629] ankylosing spondylitis
Sagopilone
go.drugbank.com/drugs/DB12391Investigationalmultidrug-resistant and paclitaxel-resistant tumor cell lines in vitro and in vivo. … Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others.