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Verzistobart
go.drugbank.com/drugs/DB18895InvestigationalVerzistobart is under investigation in clinical trial NCT06056895 (Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma).
CFG-920
go.drugbank.com/drugs/DB19193InvestigationalCFG-920 is under investigation in clinical trial NCT04060394 (Dose-escalation and Efficacy Study of Lae001/prednisone Plus Afuresertib Patients With M-crpc).
Mericitabine
go.drugbank.com/drugs/DB12045InvestigationalMericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of PSI-6130, which demonstrated excellent potency in preclinical studies. … PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an enzyme that is necessary for hepatitis C viral replication.
5alpha-androstane-3beta,17alpha-diol
go.drugbank.com/drugs/DB03926ExperimentalIt has been implicated as a regulator of gonadotropin secretion. … 5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite of [testosterone] with androgenic activity.
Human growth hormone-releasing peptide 3
go.drugbank.com/drugs/DB19227InvestigationalHuman growth hormone-releasing peptide 3 is under investigation in clinical trial NCT00846872 (Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance
Synonyms: L-argininamide, 2-methylalanyl-d-tryptophyl-d-prolyl-d-isoleucyl-3-Methyl-5-(7-{4-[(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenoxy}heptyl)-1,2-oxazole
go.drugbank.com/drugs/DB08727Experimental3-Methyl-5-(7-{4-[(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenoxy}heptyl)-1,2-oxazole is a solid. This compound belongs to the phenol ethers. … These are aromatic compounds containing an ether group substituted with a benzene ring. 3-Methyl-5-(7-{4-[(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenoxy}heptyl)-1,2-oxazole is known to target genome
Synonyms: 3-Methyl-5-(7-{4-[(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenoxy}heptyl)-1,2-oxazoleInactivated SARS-CoV-2 Vaccine (Chinese Academy of Medical Sciences)
go.drugbank.com/drugs/DB15863ExperimentalThe SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and is inactivated in Vero Cells[A219758]. … This vaccine specifically was developed in collaboration with the Chinese Academy of Medical Sciences, West China Second University Hospital, and Yunan Center for Disease Control and Prevention.
Dimethyltryptamine
go.drugbank.com/drugs/DB01488IllicitInvestigationalAn N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. … It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
Escin
go.drugbank.com/drugs/DB15907InvestigationalSodium aescinate is under investigation in clinical trials for its potential to treat cerebral conditions, including NCT04247659 (studying the relationship between asymmetric vascular sign of cortex and … prognosis in massive cerebral infarction) and NCT05263167 (aimed at reducing edema after intracerebral hemorrhage).
Tocofibrate
go.drugbank.com/drugs/DB19752ExperimentalTocofibrate is a small molecule drug. … The usage of the INN stem '-fibrate' in the name indicates that Tocofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.