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Displaying results 9781 - 9790 of 10000 in total
  1. Drug

    Rovalpituzumab tesirine

    go.drugbank.com/drugs/DB13017
    Investigational

    Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others.

  2. Drug

    PEP0101

    go.drugbank.com/drugs/DB18572
    Experimental

    PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.

    Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.
  3. Drug

    TN-201

    go.drugbank.com/drugs/DB18700
    Investigational

    TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.

  4. Drug

    MRK-003

    go.drugbank.com/drugs/DB17015
    Experimental

    It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]

    Synonyms: (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide
  5. Drug

    JLK-247

    go.drugbank.com/drugs/DB17637
    Experimental

    JLK-247 is an adeno-associated viral vector serotype 9 (AAV9)-mediated gene replacement therapy for the treatment of Sanfilippo Syndrome Type C or MPS IIIC.[L46686]

  6. Drug

    CS1 CAR-T

    go.drugbank.com/drugs/DB33915
    Experimental

    CS1 CAR-T is under investigation in clinical trial NCT07809594 (CS1-Targeted CAR-T Cells for Relapsed/Refractory Multiple Myeloma).

  7. Drug

    ATX-201

    go.drugbank.com/drugs/DB05765
    Investigational

    ATX-201 is one of a family of novel compounds that inhibits microtubule polymerization. It is developed by Kythera Biopharmaceuticals, Inc. for the treatment of actinic keratosis. The company announced the decision to discontinue its ATX...

  8. Drug

    PPL-100

    go.drugbank.com/drugs/DB05961
    Investigational

  9. Drug

    BIIB015

    go.drugbank.com/drugs/DB06304
    Investigational

    BIIB015 is a humanized, IgG1 [immunoglobulin G 1], DM4-Conjugated, anti-cripto, monoclonal antibody. It has been investigated for the treatment of subjects with relapsed or refractory solid tumours.

  10. Drug

    Evernimicin

    go.drugbank.com/drugs/DB06431
    Experimental