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Saracatinib
go.drugbank.com/drugs/DB11805InvestigationalSaracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.
Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 1-RingNifurtimox
go.drugbank.com/drugs/DB11820ApprovedInvestigationalChagas disease, caused by a parasite known as Trypanosoma cruzi (T.cruzi), is a vector-transmitted disease affecting animals and humans in the Americas. … [L15366] The CDC estimates that approximately 8 million people in Central America, South America, and Mexico are infected with T. cruzi, without symptoms.
Categories: Heterocyclic Compounds, 1-RingNeratinib
go.drugbank.com/drugs/DB11828ApprovedInvestigationalNeratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 奈拉替尼Dinitrochlorobenzene
go.drugbank.com/drugs/DB11831InvestigationalDinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.
Synonyms: 1-chloro-2,4-dinitrobenzeneCategories: Compounds used in a research, industrial, or household settingBasimglurant
go.drugbank.com/drugs/DB11833InvestigationalBasimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.
Categories: Heterocyclic Compounds, 1-RingOsilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigationalCushing's disease is often the result of ACTH hypersecretion secondary to a pituitary tumor, and surgical resection of the tumour is generally the treatment of choice. … [L12123] It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder in which cortisol levels are chronically and supraphysiologically elevated.
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesEntinostat
go.drugbank.com/drugs/DB11841InvestigationalEntinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.
Synonyms: N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide, N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl esterCategories: Heterocyclic Compounds, 1-RingAngiotensin II
go.drugbank.com/drugs/DB11842ApprovedInvestigationalShock is the inability to maintain blood flow to vital tissues and the potential resultant organ failure and death within hours, no matter young or o ld. … As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a vasoconstrictor to increase blood pressure
Synonyms: 5-L-isoleucineangiotensin II, 5-isoleucine-angiotensin IIPesampator
go.drugbank.com/drugs/DB11843InvestigationalPF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural.
Categories: Heterocyclic Compounds, 1-RingCreatinine
go.drugbank.com/drugs/DB11846InvestigationalCreatinine has been used in trials studying the treatment of Amyotrophic Lateral Sclerosis.
Categories: Heterocyclic Compounds, 1-Ring