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Pemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalPemigatinib is a small molecule kinase inhibitor with antitumour activity. … growth factor receptor 2 (FGFR2) gene fusion or other rearrangements as detected by an FDA-approved test.
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesTelisotuzumab vedotin
go.drugbank.com/drugs/DB15104ApprovedInvestigationalTelisotuzumab vedotin is an antibody-drug conjugate comprising [telisotuzumab], a c-Met-directed humanized IgG1κ monoclonal antibody, conjugated to monomethyl auristatin E (MMAE), a small molecule microtubule-disrupting … agent, via a protease-cleavable valine-citrulline linker.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsFludeoxyglucose
go.drugbank.com/drugs/DB15107InvestigationalFludeoxyglucose is under investigation in clinical trial NCT03262389 (Comparison of F-18 FDG and C-11 Acetate PET in Multiple Myeloma).
Transfluthrin
go.drugbank.com/drugs/DB15117InvestigationalTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
Categories: Compounds used in a research, industrial, or household settingPCS-499
go.drugbank.com/drugs/DB15122InvestigationalPCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients).
Categories: Heterocyclic Compounds, 2-RingSynonyms: Deuterated S-lisofyllinePonezumab
go.drugbank.com/drugs/DB15135InvestigationalPonezumab is under investigation in clinical trial NCT00607308 (A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease).
Rebaudioside A
go.drugbank.com/drugs/DB15136InvestigationalRebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus).
Synonyms: Rebaudioside ABifunctional epoxide hydrolase 2
go.drugbank.com/drugs/DB15139InvestigationalBifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients
Synonyms: Bifunctional epoxide hydrolase 2Tinostamustine
go.drugbank.com/drugs/DB15147InvestigationalTinostamustine is under investigation in clinical trial NCT03452930 (Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma).
Categories: Heterocyclic Compounds, 2-RingTMC-649128
go.drugbank.com/drugs/DB15152InvestigationalTMC-649128 is under investigation in clinical trial NCT01391117 (TMC649128HPC1002 - a Trial inGenotype 1 Hepatitis C Virus (HCV) - Infected Participants to Determine the Safety, Tolerability, Pharmacokinetics