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Displaying results 9831 - 9840 of 10000 in total
  1. Drug

    Inarigivir

    go.drugbank.com/drugs/DB15062
    Investigational

    Inarigivir is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B

  2. Drug

    PF-06291874

    go.drugbank.com/drugs/DB15065
    Investigational

    PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Agerafenib

    go.drugbank.com/drugs/DB15068
    Investigational

    Agerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).

    Categories: Heterocyclic Compounds, 2-Ring, Proto-Oncogene Proteins B-raf, antagonists & inhibitors
  4. Drug

    ELX-02

    go.drugbank.com/drugs/DB15080
    Investigational

    ELX-02 is under investigation in clinical trial NCT03309605 (Phase 1 Study of ELX-02 in Healthy Adult Subjects).

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    18-methoxycoronaridine

    go.drugbank.com/drugs/DB15096
    Investigational

    18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Cusatuzumab

    go.drugbank.com/drugs/DB15100
    Investigational

    [A241975] Cusatuzumab is a humanized IgG1 antibody targeted against CD70. … An overexpression of CD70 can result in the proliferation of malignant cells and has been documented in a variety of solid and hematological malignancies.

  7. Drug

    Pemigatinib

    go.drugbank.com/drugs/DB15102
    ApprovedInvestigational

    Pemigatinib is a small molecule kinase inhibitor with antitumour activity. … growth factor receptor 2 (FGFR2) gene fusion or other rearrangements as detected by an FDA-approved test.

    Categories: MATE 1 Inhibitors, Cytochrome P-450 Substrates
  8. Drug

    Telisotuzumab vedotin

    go.drugbank.com/drugs/DB15104
    ApprovedInvestigational

    Telisotuzumab vedotin is an antibody-drug conjugate comprising [telisotuzumab], a c-Met-directed humanized IgG1κ monoclonal antibody, conjugated to monomethyl auristatin E (MMAE), a small molecule microtubule-disrupting … agent, via a protease-cleavable valine-citrulline linker.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  9. Drug

    Fludeoxyglucose

    go.drugbank.com/drugs/DB15107
    Investigational

    Fludeoxyglucose is under investigation in clinical trial NCT03262389 (Comparison of F-18 FDG and C-11 Acetate PET in Multiple Myeloma).

  10. Drug

    Transfluthrin

    go.drugbank.com/drugs/DB15117
    Investigational

    Transfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).

    Categories: Compounds used in a research, industrial, or household setting