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LAVA-051
go.drugbank.com/drugs/DB18395InvestigationalLAVA-051 is a humanized Vγ9Vδ2-T cell-engaging bispecific antibody.
IFx-Hu2.0
go.drugbank.com/drugs/DB18396InvestigationalIt is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Synonyms: Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI® polymer-based reagent linearKP1237
go.drugbank.com/drugs/DB18401ExperimentalKP1237 is a antibody-redirecting molecule composed of two binding sites (a CD38 binder and a universal antibody binding terminus binder) connected by a linker chain.
rAAV9-hNAGLU
go.drugbank.com/drugs/DB18415ExperimentalrAAV9-hNAGLU consists of a recombinant AAV9 expressing human alpha-N-acetylglucosaminidase.
PF-05230907
go.drugbank.com/drugs/DB18417InvestigationalPF-05230907 is a recombinant activated Factor X variant.
RC118
go.drugbank.com/drugs/DB18428InvestigationalRC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Synonyms: Recombinant humanized anti-MSLN monoclonal antibody- monomethyl auristatin E conjugateAGTC-402
go.drugbank.com/drugs/DB18433InvestigationalAGTC-402 is a recombinant adeno-associated virus vector expressing the cyclic nucleotide gated channel alpha subunit (CNGA3).
Synonyms: rAAV2tYF-PR.1-hCNGA3SEL-302
go.drugbank.com/drugs/DB18434InvestigationalSEL-302 is a recombinant adeno-associated virus vector-based gene therapy expressing the methylmalonyl-CoA mutase (MMUT) transgene.
Maplirpacept
go.drugbank.com/drugs/DB18441InvestigationalMaplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Synonyms: 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human γ4-chain C region C-terminal fragment), dimerCC-90001
go.drugbank.com/drugs/DB18445InvestigationalSynonyms: 2-((1,1-DIMETHYLETHYL)AMINO)-4-(((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYL)AMINO)-5-PYRIMIDINECARBOXAMIDE, 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDECategories: MATE 1 Inhibitors, MATE 2 Inhibitors