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Displaying results 1 - 10 of 10000 in total
  1. Drug

    Deanol

    go.drugbank.com/drugs/DB13352
    Investigational

    Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups. … Deanol has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.

    Categories: deanolSynonyms: 2-(dimethylamino)ethanol, Deanol
  2. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms

    Mixtures: DEXANETİL % 0,1 + % 0,3 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, R-DIM®Categories: P-glycoprotein inducers, P-glycoprotein inhibitors
  3. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).

    Synonyms: [2-(2,6-dichloroanilino)phenyl]acetic acid, 2-((2,6-dichlorophenyl)amino)benzeneacetic acidSalts: Diclofenac deanol
  4. Drug

    Somatrem

    go.drugbank.com/drugs/DB09098
    ApprovedWithdrawn

    Such discussion revolves around whether patients' natural disposition of short stature should be considered a medical condition justifying medical treatment with such hormone therapy - especially when

  5. Drug

    Asfotase alfa

    go.drugbank.com/drugs/DB09105
    ApprovedInvestigational

    Asfotase Alfa is marketed under the brand name Strensiq® by Alexion Pharmaceuticals, Inc. The annual average price of Asfotase Alfa treatment is $285,000. … Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP).

  6. Drug

    Pentastarch

    go.drugbank.com/drugs/DB09111
    ApprovedWithdrawn

    When administered, pentastarch remains mainly in the circulatory system and hence, it is considered a plasma expander.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Stiripentol

    go.drugbank.com/drugs/DB09118
    ApprovedInvestigational

    Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs. The clinical development and marketing of stiripentol were first delayed due to the drug's...

    Synonyms: 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol, 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-olCategories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitors
  8. Drug

    Aurothioglucose

    go.drugbank.com/drugs/DB09121
    ApprovedWithdrawn

    Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression...

    International brands: Solganal B
  9. Drug

    Dienogest

    go.drugbank.com/drugs/DB09123
    ApprovedInvestigational

    It is a derivative of 19-nortestosterone and has antiandrogenic properties. … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.

    Mixtures: Foxinette 0,03 mg/2 mg 21+7 - Filmtabletten, Velbienne 1 mg/2 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Uridine triacetate

    go.drugbank.com/drugs/DB09144
    Approved

    It reduces toxicity and cell-death associated with two cytotoxic intermediates: 5-fluoro-2'-deoxyuridine-5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). … As a result of UMPS deficiency, patients experience a systemic deficiency of pyrimidine nucleotides, accounting for most symptoms of the disease.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2',3',5'-tri-O-acetyluridine, 2',3',5'-Triacetyluridine